Evidence map›Paper›PMID 29527430›Full record

ArticleBeilstein journal of nanotechnology2018

Green synthesis of fluorescent carbon dots from spices for in vitro imaging and tumour cell growth inhibition.

Nagamalai Vasimalai, Vânia Vilas-Boas, Juan Gallo, María de Fátima Cerqueira, Mario Menéndez-Miranda, José Manuel Costa-Fernández, Lorena Diéguez, Begoña Espiña, María Teresa Fernández-Argüelles

Open access · diamondAbstract read
In one paragraph

Article in Beilstein journal of nanotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 190 citations in OpenAlex.

  1. Review
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  9. Recent Biomedical Applications of Carbon Quantum Dots in Cancer Treatment.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024
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  18. Nanoformulation ofACS omega · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Nagamalai Vasimalai *Life Sciences Department, International Iberian Nanotechnology Laboratory (INL), Avenida Mestre José Veiga, 4715-330 Braga, Portugal.
Vânia Vilas-Boas *Life Sciences Department, International Iberian Nanotechnology Laboratory (INL), Avenida Mestre José Veiga, 4715-330 Braga, Portugal.ORCID 0000-0002-4798-2158
Juan GalloLife Sciences Department, International Iberian Nanotechnology Laboratory (INL), Avenida Mestre José Veiga, 4715-330 Braga, Portugal.ORCID 0000-0002-2028-3234
María de Fátima CerqueiraCenter of Physics, University of Minho, 4710-057 Braga, Portugal.
Mario Menéndez-MirandaDepartment of Physical and Analytical Chemistry, University of Oviedo Julian Clavería 8, 33006 Oviedo, Spain.
José Manuel Costa-FernándezDepartment of Physical and Analytical Chemistry, University of Oviedo Julian Clavería 8, 33006 Oviedo, Spain.ORCID 0000-0002-8671-5300
Lorena DiéguezLife Sciences Department, International Iberian Nanotechnology Laboratory (INL), Avenida Mestre José Veiga, 4715-330 Braga, Portugal.ORCID 0000-0003-3695-6963
Begoña EspiñaLife Sciences Department, International Iberian Nanotechnology Laboratory (INL), Avenida Mestre José Veiga, 4715-330 Braga, Portugal.ORCID 0000-0002-7645-2834
María Teresa Fernández-ArgüellesLife Sciences Department, International Iberian Nanotechnology Laboratory (INL), Avenida Mestre José Veiga, 4715-330 Braga, Portugal.ORCID 0000-0002-5191-3024
International Iberian Nanotechnology Laboratory · PTUniversidad de Oviedo · ESUniversidade do Porto · PTUniversity of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon dots have demonstrated great potential as luminescent nanoparticles in bioapplications. Although such nanoparticles appear to exhibit low toxicity compared to other metal luminescent nanomaterials, today we know that the toxicity of carbon dots (C-dots) strongly depends on the protocol of fabrication. In this work, aqueous fluorescent C-dots have been synthesized from cinnamon, red chilli, turmeric and black pepper, by a one-pot green hydrothermal method. The synthesized C-dots were firstly characterized by means of UV-vis, fluorescence, Fourier transform infrared and Raman spectroscopy, dynamic light scattering and transmission electron microscopy. The optical performance showed an outstanding ability for imaging purposes, with quantum yields up to 43.6%. Thus, the cytotoxicity of the above mentioned spice-derived C-dots was evaluated in vitro in human glioblastoma cells (LN-229 cancer cell line) and in human kidney cells (HK-2 non-cancerous cell line). Bioimaging and viability studies were performed with different C-dot concentrations from 0.1 to 2 mg·mL

Indexed as

bioimagingcarbon quantum dotsfluorescencespices

Identifiers

PMID29527430
PMCPMC5827765
OpenAlexW2786192136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.