ArticleBMJ open diabetes research & care2018
Development and validation of a prediction model for insulin-associated hypoglycemia in non-critically ill hospitalized adults.
Article in BMJ open diabetes research & care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Data-based modeling for hypoglycemia prediction: Importance, trends, and implications for clinical practice.Frontiers in public health · 2023Pooled it
- 16. Diabetes Care in the Hospital: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- Comparison of logistic regression and artificial neural network models for predicting hypoglycemia in non-ICU inpatients with diabetes.BMC endocrine disorders · 2025Article
- Development and validation of a machine learning model for real-time blood glucose prediction for ICU patients.BMC medical informatics and decision making · 2025Article
- Challenges with Implementing Predictive Models for Inpatient Hypoglycemic Events in Clinical Decision Support.Applied clinical informatics · 2025Article
- Identification and Validation of Biomarkers to Predict Early Diagnosis of Inflammatory Bowel Disease and Its Progression to Colorectal Cancer.Biochemical genetics · 2025Article
- Towards a prescribing monitoring system for medication safety evaluation within electronic health records: a scoping review.BMC medical informatics and decision making · 2025Article
- Association Between Daily Insulin Dose Adjustments and Glycemic Control in Noncritically Ill Hospitalized Hyperglycemic Patients: A Retrospective Cohort Study.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025Article
- 16. Diabetes Care in the Hospital: Standards of Care in Diabetes-2025.Diabetes care · 2025Review
- Artificial Intelligence to Diagnose Complications of Diabetes.Journal of diabetes science and technology · 2025Review
- Machine learning-based online prediction of nocturnal hypoglycemia in elderly patients with type 2 diabetes.Frontiers in endocrinology · 2025Article
- Development and Validation of a Nocturnal Hypoglycaemia Risk Model for Patients With Type 2 Diabetes Mellitus.Nursing open · 2024Article
- Development and Validation of Inpatient Hypoglycemia Models Centered Around the Insulin Ordering Process.Journal of diabetes science and technology · 2024Article
- Nomogram for Predicting Hypoglycemia in Type 2 Diabetes Mellitus Patients Treated with Insulin Pump During Enteral Nutrition.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- 16. Diabetes Care in the Hospital: Standards of Care in Diabetes-2024.Diabetes care · 2024Review
- Comparative Analysis of Predictive Interstitial Glucose Level Classification Models.Sensors (Basel, Switzerland) · 2023Article
- Prediction of Next Glucose Measurement in Hospitalized Patients by Comparing Various Regression Methods: Retrospective Cohort Study.JMIR formative research · 2023Article
- Artificial Intelligence for Predicting and Diagnosing Complications of Diabetes.Journal of diabetes science and technology · 2023Article
- 16. Diabetes Care in the Hospital: Standards of Care in Diabetes-2023.Diabetes care · 2023Review
- Predicting hypoglycemia in critically Ill patients using machine learning and electronic health records.Journal of clinical monitoring and computing · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo develop and validate a multivariable prediction model for insulin-associated hypoglycemia in non-critically ill hospitalized adults. RESEARCH DESIGN AND
methodsWe collected pharmacologic, demographic, laboratory, and diagnostic data from 128 657 inpatient days in which at least 1 unit of subcutaneous insulin was administered in the absence of intravenous insulin, total parenteral nutrition, or insulin pump use (index days). These data were used to develop multivariable prediction models for biochemical and clinically significant hypoglycemia (blood glucose (BG) of ≤70 mg/dL and <54 mg/dL, respectively) occurring within 24 hours of the index day. Split-sample internal validation was performed, with 70% and 30% of index days used for model development and validation, respectively.
resultsUsing predictors of age, weight, admitting service, insulin doses, mean BG, nadir BG, BG coefficient of variation (CV
conclusionsHospitalized patients at risk of insulin-associated hypoglycemia can be identified using validated prediction models, which may support the development of real-time preventive interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.