Evidence map›Paper›PMID 29527166›Full record

ArticleFrontiers in pharmacology2018

Icariin Ameliorate Thiram-Induced Tibial Dyschondroplasia via Regulation of WNT4 and VEGF Expression in Broiler Chickens.

Hui Zhang, Khalid Mehmood, Kun Li, Mujeeb U Rehman, Xiong Jiang, Shucheng Huang, Lei Wang, Lihong Zhang, Xiaole Tong, Fazul Nabi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
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  6. Review
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  8. Total Flavonoids ofFrontiers in pharmacology · 2022
    Article
  9. Article
  10. LPS-induced inflammation disorders bone modeling and remodeling by inhibiting angiogenesis and disordering osteogenesis in chickens.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2020
    Article
  11. Ameliorative effect of naringin against thiram-induced tibial dyschondroplasia in broiler chicken.Environmental science and pollution research international · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Effect of Total Flavonoids ofFrontiers in pharmacology · 2018
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Hui ZhangCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Khalid MehmoodCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Kun LiCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Mujeeb U RehmanCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Xiong JiangCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Shucheng HuangCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Lei WangCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Lihong ZhangCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Xiaole TongCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Fazul NabiCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Wangyuan YaoCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Muhammad K IqbalCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Muhammad ShahzadCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Jiakui LiCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Huazhong Agricultural University · CNIslamia University of Bahawalpur · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tibial dyschondroplasia (TD) is main bone problem in fast growing poultry birds that effect proximal growth plate (GP) of tibia bone. TD is broadly defined as non-vascularized and non-mineralized, and enlarged GP with tibia bone deformation and lameness. Icariin (

Indexed as

icariinthiramtibial dyschondroplasiaVEGFWNT4

Identifiers

PMID29527166
PMCPMC5829035
OpenAlexW2790723803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.