Evidence map›Paper›PMID 29527157›Full record

ReviewFrontiers in human neuroscience2018

Computational Neuropsychology and Bayesian Inference.

Thomas Parr, Geraint Rees, Karl J Friston

Abstract readReview
In one paragraph

Review in Frontiers in human neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Trial
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  3. Review
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  6. Article
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  11. Review
  12. Article
  13. Precision neuropsychology in the area of AI.Frontiers in psychology · 2025
    Article
  14. The Many Roles of Precision in Action.Entropy (Basel, Switzerland) · 2024
    Review
  15. Article
  16. Review
  17. A model of time-varying music engagement.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  18. Article
  19. Article
  20. Digital Being: social media and the predictive mind.Neuroscience of consciousness · 2024
    Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thomas ParrWellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, United Kingdom.
Geraint ReesWellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, United Kingdom.
Karl J FristonWellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, United Kingdom.

Funding

Wellcome Trust 100227
6 · The paper itself

Abstract

Computational theories of brain function have become very influential in neuroscience. They have facilitated the growth of formal approaches to disease, particularly in psychiatric research. In this paper, we provide a narrative review of the body of computational research addressing neuropsychological syndromes, and focus on those that employ Bayesian frameworks. Bayesian approaches to understanding brain function formulate perception and action as inferential processes. These inferences combine 'prior' beliefs with a generative (predictive) model to explain the causes of sensations. Under this view, neuropsychological deficits can be thought of as false inferences that arise due to aberrant prior beliefs (that are poor fits to the real world). This draws upon the notion of a Bayes optimal pathology - optimal inference with suboptimal priors - and provides a means for computational phenotyping. In principle, any given neuropsychological disorder could be characterized by the set of prior beliefs that would make a patient's behavior appear Bayes optimal. We start with an overview of some key theoretical constructs and use these to motivate a form of computational neuropsychology that relates anatomical structures in the brain to the computations they perform. Throughout, we draw upon computational accounts of neuropsychological syndromes. These are selected to emphasize the key features of a Bayesian approach, and the possible types of pathological prior that may be present. They range from visual neglect through hallucinations to autism. Through these illustrative examples, we review the use of Bayesian approaches to understand the link between biology and computation that is at the heart of neuropsychology.

Indexed as

active inferencecomputational phenotypingneuropsychologyprecisionpredictive coding

Identifiers

PMID29527157
PMCPMC5829460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.