ArticleJournal of applied biobehavioral research2017
The Complex Relationship between Pain Intensity and Physical Functioning in Fibromyalgia: The Mediating Role of Depression.
Article in Journal of applied biobehavioral research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Pooled it
- Brain compensatory mechanisms in depression and memory complaints in fibromyalgia: the role of theta oscillatory activity.Pain medicine (Malden, Mass.) · 2024Trial
- In the End: Associations Between Sleep Disturbance and Functional Impairment in Fibromyalgia-A Path Analysis Study.Journal of sleep research · 2026Article
- Pain-related disability in functional neurological disorder (FND): the role of pain intensity and psychological factors.Journal of neurology · 2026Article
- Whole-Body Cryostimulation in Complex Regional Pain Syndrome: A Case Study.Journal of clinical medicine · 2026Article
- The Role of Subjective Well-Being in the Relationship Between Illness Invalidation, Acceptance, and Functioning in Fibromyalgia.Behavioral sciences (Basel, Switzerland) · 2026Article
- The Mediating Role of Depression in the Relationship Between Perceived Injustice and Pain Intensity Among Fibromyalgia Patients.Journal of pain research · 2025Article
- The Fibromyalgia Decomposition Phenomenon: A Reflexive Thematic Analysis.Behavioral sciences (Basel, Switzerland) · 2024Article
- Visuotactile integration in individuals with fibromyalgia.Frontiers in human neuroscience · 2024Article
- The Effects of Mindfulness Interventions on Fibromyalgia in Adults aged 65 and Older: A Window to Effective Therapy.Journal of clinical psychology in medical settings · 2023Review
- Predictors of Multiwave Opioid Use Among Older American Adults.Innovation in aging · 2023Article
- In the Shoulder or in the Brain? Behavioral, Psychosocial and Cognitive Characteristics of Unilateral Chronic Shoulder Pain with Symptoms of Central Sensitization.Healthcare (Basel, Switzerland) · 2022Article
- Catastrophizing, Kinesiophobia, and Acceptance as Mediators of the Relationship Between Perceived Pain Severity, Self-Reported and Performance-Based Physical Function in Women with Fibromyalgia and Obesity.Journal of pain research · 2022Article
- Meditative-based diaphragmatic breathing vs. vagus nerve stimulation in the treatment of fibromyalgia-A randomized controlled trial: Body vs. machine.Frontiers in neurology · 2022Article
- Distress as a mediator for pain and activities of daily living in older adults with fibromyalgia.Frontiers in medicine · 2022Article
- Contextualizing goal preferences in fear-avoidance models. Looking at fatigue as a disabling symptom in fibromyalgia patients.PloS one · 2021Article
- Use of Complementary and Integrative Therapies by Fibromyalgia Patients: A 14-Year Follow-up Study.Mayo Clinic proceedings. Innovations, quality & outcomes · 2019Article
- Psychological impact of fibromyalgia: current perspectives.Psychology research and behavior management · 2019Review
- Cognitive-Behavioral and Personal Construct Therapies for Depression in Women with Fibromyalgia: A Randomized Controlled Trial.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
purposeFibromyalgia (FM) is typically associated with the experience of diffuse pain and physical impairment. Depression also commonly co-exists in patients with FM, and has been correlated with pain intensity and physical functioning. Previous research suggests an association between pain intensity and physical functioning; however, the direct causal relationship between improvements in pain intensity and in functioning is not observed in many FM patients. This may suggest that another factor such as depression is mediating this relationship. The present work examined mediating role of depression.
methods216 patients with FM completed measures of pain intensity, depression, and physical function as part of a larger longitudinal study. Assessments were completed at baseline, 12, 24, and 36 weeks.
resultsLongitudinal mediational analyses indicated that depression is a partial mediator of the relationship between pain intensity and physical functioning at all four assessment points. Beta coefficients for the path from pain to physical functioning ranged from 0.18 - 0.36, with attenuated path coefficients ranging from 0.03 - 0.08, still showing significant but decreased associations when depression was added as a mediator.
conclusionsClinical implication includes the importance of treating co-morbid depression in patients with fibromyalgia early in the course of treatment to prevent engagement in the cycle of disability.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.