Evidence map›Paper›PMID 29526962›Full record

ArticleInternal medicine (Tokyo, Japan)2018

Successful Cord Blood Stem Cell Transplantation for Primary Cutaneous CD8-positive Aggressive Epidermotropic Cytotoxic T-cell Lymphoma Complicated with Cerebral Infiltration.

Satoshi Ichikawa, Noriko Fukuhara, Shunsuke Hatta, Masahito Himuro, Hiroki Katsushima, Kentaro Nasu, Koya Ono, Kyoko Inokura, Masahiro Kobayashi, Yasushi Onishi and 4 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Satoshi IchikawaDepartment of Hematology and Rheumatology, Tohoku University Hospital, Japan.
Noriko FukuharaDepartment of Hematology and Rheumatology, Tohoku University Hospital, Japan.
Shunsuke HattaDepartment of Hematology and Rheumatology, Tohoku University Hospital, Japan.
Masahito HimuroDepartment of Hematology and Rheumatology, Tohoku University Hospital, Japan.
Hiroki KatsushimaDepartment of Hematopathology, Tohoku University Hospital, Japan.
Kentaro NasuDepartment of Hematology and Rheumatology, Tohoku University Hospital, Japan.
Koya OnoDepartment of Hematology and Rheumatology, Tohoku University Hospital, Japan.
Kyoko InokuraDepartment of Hematology and Cell Therapy, Yamagata University Faculty of Medicine, Japan.
Masahiro KobayashiDepartment of Hematology and Rheumatology, Tohoku University Hospital, Japan.
Yasushi OnishiDepartment of Hematology and Rheumatology, Tohoku University Hospital, Japan.
Hiroshi FujiiDepartment of Hematology and Rheumatology, Tohoku University Hospital, Japan.
Kenichi IshizawaDepartment of Hematology and Cell Therapy, Yamagata University Faculty of Medicine, Japan.
Ryo IchinohasamaDepartment of Hematopathology, Tohoku University Hospital, Japan.
Hideo HarigaeDepartment of Hematology and Rheumatology, Tohoku University Hospital, Japan.
Tohoku University Hospital · JPYamagata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 16-year-old boy, who had been initially examined for bilateral blepharedema and slight eruption, presented with rapidly deteriorating symptoms in associating with headache and consciousness disturbance. He was diagnosed to have primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma (PCAE-CTL) by a biopsy of the skin and brain. After whole-brain radiation and some courses of chemotherapy, cord blood transplantation was performed with myeloablative conditioning. After transplantation, the cerebral dysfunction gradually improved. Disease remission was confirmed by the disappearance of any abnormal findings on electroencephalogram and magnetic resonance imaging. PCAE-CTL is reported to be an extremely aggressive disease with a poor prognosis, but the timely performance of cord blood transplantation is considered to be a promising treatment strategy.

Indexed as

AdolescentBiopsyBrain NeoplasmsCD8-Positive T-LymphocytesCord Blood Stem Cell TransplantationHumansLymphoma, T-Cell, CutaneousMaleSkinSkin Neoplasmscerebral infiltrationcord blood transplantationprimary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma

Identifiers

PMID29526962
PMCPMC6096016
OpenAlexW2793261599

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.