SynthesisJournal of epidemiology2018
Observational Evidence of the Association Between Handgrip Strength, Hand Dexterity, and Cognitive Performance in Community-Dwelling Older Adults: A Systematic Review.
Synthesis in Journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Instruments for measuring the neuromuscular function domain of vitality capacity in older persons: an umbrella review.European geriatric medicine · 2024Pooled it
- The influence of eight cognitive training regimes upon cognitive screening tool performance in post-stroke survivors: a network meta-analysis.Frontiers in aging neuroscience · 2024Pooled it
- Handgrip strength and risk of cognitive outcomes: new prospective study and meta-analysis of 16 observational cohort studies.GeroScience · 2022Pooled it
- The Effects of the MONOZUKURI Program on Executive Function Among Community-Dwelling Older Adults: A Randomized Controlled Trial.Brain and behavior · 2025Trial
- Can Muscle Mass Be Maintained with A Simple Resistance Intervention in the Older People? A Cluster Randomized Controlled Trial in Thailand.International journal of environmental research and public health · 2021Trial
- Exploring the relative contributions of multiple modifiable physical health variables to executive function and episodic memory performance in older adults.Neuropsychology · 2026Article
- Exploring the longitudinal course of motor dexterity in first-episode psychosis: a 10-year follow-up.European archives of psychiatry and clinical neuroscience · 2026Article
- Long-term patterns of depressive symptoms and cognitive aging in middle-aged and older adults.Archives of public health = Archives belges de sante publique · 2026Article
- Limited Evidence to Review-Is There an Association Between Cognition and Upper Extremity Motor Reaction Time in Older Adults?NeuroSci · 2025Review
- The Experience of and Needs for Exergames in Older Adults With Mild Cognitive Impairment: Qualitative Interview Study.JMIR serious games · 2025Article
- Muscle dysfunction is associated with poor quality of life in long-term controlled patients with acromegaly.Pituitary · 2025Article
- Quantifying Mild Cognitive Impairments in Older Adults Using Multi-modal Wearable Sensor Data in a Kitchen Environment.medRxiv : the preprint server for health sciences · 2025Article
- Oral health implications in Parkinson's disease.NPJ Parkinson's disease · 2025Review
- Hand grip strength and quality of life among adults aged 50-90 years from South West Poland.Scientific reports · 2025Article
- Hand dexterity and mobility independently predict cognition in older adults: a multi-domain regression analysis.Frontiers in aging neuroscience · 2025Article
- Handgrip strength is associated with cognitive function in patients with head injury with loss of consciousness: results from the NHANES 2011-2014.Frontiers in neurology · 2025Article
- The Temporal Relation of Physical Function with Cognition and the Influence of Brain Health in the Oldest-Old.Gerontology · 2025Article
- The role of dynapenia and obesity on cognitive function in older adults.Clinical nutrition ESPEN · 2024Article
- The Association between Physical Frailty and Cognitive Performance in Older Adults Aged 60 to 96 Years: Data from the "Good Aging in Skåne" (GÅS) Swedish Population Study.Annals of geriatric medicine and research · 2024Article
- Identifying characteristics and clinical conditions associated with hand grip strength in adults: the Project Baseline Health Study.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDeterioration of hand motor function is a possible risk factor of cognitive impairment in older adults. Despite a growing body of research, a lack of clarity exists regarding the relationships. This review offers a synthesis of existing observational studies evaluating the associations of handgrip strength and hand dexterity with cognitive performance in community-dwelling older adults.
methodsPubMed, PsycINFO, and ScienceDirect were systematically searched (search dates: 1990-2016), and relevant articles were cross-checked for related and relevant publications.
resultsTwenty-two observational studies assessed the association of handgrip strength or hand dexterity with cognitive performance; none evaluated handgrip strength and hand dexterity together. Handgrip strength was associated with global cognition, mostly assessed using the Mini-Mental State Examination, cross-sectionally and longitudinally. Also, one cross-sectional and three longitudinal studies found an association with cognitive domains, such as language, memory, visuospatial ability, working memory, and processing speed. Hand dexterity was only assessed cross-sectionally in four studies. These studies found an association with cognitive domains, such as executive function.
conclusionsAlthough handgrip strength was associated with cognitive performance, it is unclear which variable at baseline affects the other in the long-term. Cross-sectional studies indicate an association between hand dexterity and cognitive performance, yet longitudinal studies are needed to elucidate this association. The interaction effects of both decreased grip strength and hand dexterity on cognitive performance is still unclear; therefore, future studies will need to consider the interaction of the three variables cross-sectionally and longitudinally.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.