Evidence map›Paper›PMID 29526762›Full record

ArticleThe Journal of investigative dermatology2018

Lack of Type 2 Innate Lymphoid Cells Promotes a Type I-Driven Enhanced Immune Response in Contact Hypersensitivity.

David A Rafei-Shamsabadi, Saskia van de Poel, Britta Dorn, Stefanie Kunz, Stefan F Martin, Christoph S N Klose, Sebastian J Arnold, Yakup Tanriver, Karolina Ebert, Andreas Diefenbach and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of investigative dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. IL-27-induced PD-L1Experimental & molecular medicine · 2024
    Article
  6. Role of Innate Immunity in Allergic Contact Dermatitis: An Update.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Contact dermatitis.Nature reviews. Disease primers · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

David A Rafei-ShamsabadiAllergy Research Group, Department of Dermatology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Saskia van de PoelAllergy Research Group, Department of Dermatology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Britta DornExperimental Dermatology and Allergy Research Group, Department of Dermatology and Allergology, University Medical Center Giessen and Marburg, Campus Giessen, Justus Liebig University, Giessen, Germany.
Stefanie KunzAllergy Research Group, Department of Dermatology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Stefan F MartinAllergy Research Group, Department of Dermatology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Christoph S N KloseInstitute of Medical Microbiology and Hygiene, University Medical Center, Freiburg, Germany.
Sebastian J ArnoldInstitute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Yakup TanriverInstitute of Medical Microbiology and Hygiene, University Medical Center, Freiburg, Germany.
Karolina EbertInstitute of Medical Microbiology and Hygiene, University Medical Center, Freiburg, Germany.
Andreas DiefenbachDepartment of Microbiology, Charité-University Medical Centre Berlin, Berlin, Germany.
Timotheus Y F HalimMedical Research Council, Laboratory of Molecular Biology, Cambridge, Cambridgeshire, UK.
Andrew N J McKenzieMedical Research Council, Laboratory of Molecular Biology, Cambridge, Cambridgeshire, UK.
Thilo JakobAllergy Research Group, Department of Dermatology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Experimental Dermatology and Allergy Research Group, Department of Dermatology and Allergology, University Medical Center Giessen and Marburg, Campus Giessen, Justus Liebig University, Giessen, Germany. Electronic address: thilo.jakob@derma.med.uni-giessen.de.
University of Freiburg · DEUniversity Medical Center Freiburg · DEUniversity of Giessen · DECharité - Universitätsmedizin Berlin · DEInstitute of Medical Microbiology and Hygiene · DEMedical Research Council · GBMRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council MC_U105178805
6 · The paper itself

Abstract

Allergic contact dermatitis and its animal model, contact hypersensitivity, are T-cell-mediated inflammatory skin diseases that require activation of the innate immune system. Here we investigate the role of innate lymphoid cells (ILCs) during the elicitation phase of 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity using Eomes

Indexed as

Adoptive TransferAnimalsDermatitis, Allergic ContactDisease Models, AnimalFemaleImmunity, InnateMaleMiceSkinT-Lymphocytes

Identifiers

PMID29526762
PMCPMC6117454
OpenAlexW2518374784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.