ArticleExperimental neurology2018
Serotonin receptor and dendritic plasticity in the spinal cord mediated by chronic serotonergic pharmacotherapy combined with exercise following complete SCI in the adult rat.
Article in Experimental neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation.CNS & neurological disorders drug targets · 2025Review
- Long-Term 5-HTInternational journal of molecular sciences · 2024Article
- Review
- A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation.Frontiers in human neuroscience · 2023Review
- Treadmill running: more 'exciting' than you think.The Journal of physiology · 2022Article
- Semaphorin7A: its role in the control of serotonergic circuits and functional recovery following spinal cord injury.Neural regeneration research · 2022Article
- Serotonin 1A Receptor Pharmacotherapy and Neuroplasticity in Spinal Cord Injury.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Phrenic motor neuron survival below cervical spinal cord hemisection.Experimental neurology · 2021Article
- Plasticity in Cervical Motor Circuits following Spinal Cord Injury and Rehabilitation.Biology · 2021Review
- Exercise-Induced Plasticity in Signaling Pathways Involved in Motor Recovery after Spinal Cord Injury.International journal of molecular sciences · 2021Review
- Article
- Activation of Neurogenesis in Multipotent Stem Cells Cultured In Vitro and in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021Article
- Three-Week Treadmill Exercise Enhances Persistent Inward Currents, Facilitates Dendritic Plasticity, and Upregulates the Excitability of Dorsal Raphe Serotonin Neurons in ePet-EYFP Mice.Frontiers in cellular neuroscience · 2020Article
- Three-week treadmill training changes the electrophysiological properties of spinal interneurons in the mice.Experimental brain research · 2019Article
- Opportunities and challenges for developing closed-loop bioelectronic medicines.Neural regeneration research · 2019Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Severe spinal cord injury (SCI) damages descending motor and serotonin (5-HT) fiber projections leading to paralysis and serotonin depletion. 5-HT receptors (5-HTRs) subsequently upregulate following 5-HT fiber degeneration, and dendritic density decreases indicative of atrophy. 5-HT pharmacotherapy or exercise can improve locomotor behavior after SCI. One might expect that 5-HT pharmacotherapy acts on upregulated spinal 5-HTRs to enhance function, and that exercise alone can influence dendritic atrophy. In the current study, we assessed locomotor recovery and spinal proteins influenced by SCI and therapy. 5-HT, 5-HT
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.