ArticleThe Journal of thoracic and cardiovascular surgery2018
Patients with anomalous aortic origin of the coronary artery remain at risk after surgical repair.
Article in The Journal of thoracic and cardiovascular surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 50 citations in OpenAlex.
- Article
- Surgical Outcomes of anomalous aortic origin of coronary arteries: early and mid-term results from a single-center experience.BMC pediatrics · 2026Article
- Risk stratification and real-world management of pediatric AAORCA: discordance between anatomical features and clinical symptoms.Frontiers in cardiovascular medicine · 2026Article
- Surgical approach and outcomes in adults with anomalous aortic origin of coronary arteries at a reference center: Outcomes of proximal coronary surgery.JTCVS open · 2025Article
- Anomalous Left Coronary Artery From the Noncoronary Sinus.CASE (Philadelphia, Pa.) · 2024Article
- Anatomical Variants of the Origin of the Coronary Arteries: A Systematic Review and Meta-Analysis of Prevalence.Diagnostics (Basel, Switzerland) · 2024Review
- Paolo Angelini's Legacy in the Study of and Treatment for Anomalous Coronary Arteries.Texas Heart Institute journal · 2023Article
- Noninvasive fractional flow reserve derived from computed tomography angiography in a patient with abnormal origin of the left main artery and cardiac death.Quantitative imaging in medicine and surgery · 2023Article
- Acute Perimyocarditis Unmasking Anomalous Coronary Artery: Is Treating the Inflammation Enough? Does Surgery Fix All?JACC. Case reports · 2022Article
- Recurrent sudden cardiac death secondary to anomalous right coronary artery: Insights into prevalence and management.SAGE open medical case reports · 2022Article
- Surgical Techniques for the Treatment of Anomalous Origin of Right Coronary Artery From the Left Sinus: A Comparative Review.Journal of the American Heart Association · 2021Review
- A Coronary Artery Anomaly Presenting as Acute Coronary Syndrome: A Case Report.The American journal of case reports · 2021Article
- Surgery for Anomalous Aortic Origin of Coronary Arteries: Technical Safeguards and Pitfalls.Frontiers in cardiovascular medicine · 2021Review
- Computed Tomography Derived Coronary Triangulated Orifice Area-Deduction of a New Parameter for Follow-up After Surgical Correction of Anomalous Aortic Origin of Coronary Arteries and Call for Validation.Frontiers in cardiovascular medicine · 2021Article
- The significance of symptoms before and after surgery for anomalous aortic origin of coronary arteries in adolescents and adults.Interactive cardiovascular and thoracic surgery · 2021Article
- Exercise-Induced Abnormalities of Regional Myocardial Deformation in Anomalous Aortic Origin of the Right Coronary Artery.World journal for pediatric & congenital heart surgery · 2020Article
- Anomalous right coronary artery with interarterial course depicting an unusual case of an electrical storm: a case presentation.BMC cardiovascular disorders · 2020Article
- Place of Angioplasty for Coronary Artery Anomalies With Interarterial Course.Frontiers in cardiovascular medicine · 2020Review
- Computed Tomography-based Patient-specific Biomechanical and Fluid Dynamic Study of Anomalous Coronary Arteries with Origin from the Opposite Sinus and Intramural Course.Heart international · 2020Review
- Diagnosis and Management of Anomalous Coronary Arteries with a Malignant Course.Interventional cardiology (London, England) · 2019Review
Corrections and comments
- Commented on byQED? Not yet!2018
- Commented on byDiscussion.2018
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesAnomalous aortic origin of a coronary artery (AAOCA) from the opposite sinus of Valsalva is a rare cardiac anomaly associated with sudden cardiac death (SCD). Single-center studies describe surgical repair as safe, although medium- and long-term effects on symptoms and risk of SCD remain unknown. We sought to describe outcomes of surgical repair of AAOCA.
methodsWe reviewed institutional records for patients who underwent AAOCA repair, from 2001 to 2016, at 2 affiliated institutions. Patients with associated heart disease were excluded.
resultsIn total, 60 patients underwent AAOCA repair. Half of the patients (n = 30) had an anomalous left coronary artery arising from the right sinus of Valsalva and half had an anomalous right. Median age at surgery was 15.4 years (interquartile range, 11.9-17.9 years; range, 4 months to 68 years). The most common presenting symptoms were chest pain (n = 38; 63%) and shortness of breath (n = 17; 28%); aborted SCD was the presenting symptom in 4 patients (7%). Follow-up data were available for 54 patients (90%) over a median of 1.6 years. Of 53 patients with symptoms at presentation, 34 (64%) had complete resolution postoperatively. Postoperative mild or greater aortic insufficiency was present in 8 patients (17%) and moderate supravalvar aortic stenosis in 1 (2%). One patient required aortic valve replacement for aortic insufficiency. Two patients required reoperation for coronary stenosis at 3 months and 6 years postoperatively.
conclusionsSurgical repair of AAOCA is generally safe and adverse events are rare. Restenosis, and even sudden cardiac events, can occur and long-term surveillance is critical. Multi-institutional collaboration is vital to identify at-risk subpopulations and refine current recommendations for long-term management.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.