Evidence map›Paper›PMID 29526247›Full record

ArticleAmerican journal of surgery2018

Burn injury mortality in patients with preexisting and new onset renal disease.

Laquanda T Knowlin, Laura Purcell, Bruce A Cairns, Anthony G Charles

Abstract read
In one paragraph

Article in American journal of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Comparative Analysis of Composite Mortality Prediction Scores in Intensive Care Burn Patients.International journal of environmental research and public health · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laquanda T KnowlinDepartment of Surgery, University of North Carolina at Chapel Hill, North Carolina Jaycee Burn Center, USA.
Laura PurcellDepartment of Surgery, University of North Carolina at Chapel Hill, North Carolina Jaycee Burn Center, USA.
Bruce A CairnsDepartment of Surgery, University of North Carolina at Chapel Hill, North Carolina Jaycee Burn Center, USA.
Anthony G CharlesDepartment of Surgery, University of North Carolina at Chapel Hill, North Carolina Jaycee Burn Center, USA. Electronic address: anthchar@med.unc.edu.

Funding

TRAUMA RESEARCH FELLOWSHIPT32GM008450 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Bruce A Cairns, Anthony G Charles · 1992 to 2026
$3.8M
NIGMS NIH HHS T32 GM008450
6 · The paper itself

Abstract

introductionWe sought to examine the impact of preexisting and new onset renal disease on burn injury mortality.

methodsRetrospective analysis of patients admitted to a regional burn center from 2002-2012 was performed. Variables analyzed included demographics, burn mechanism, inhalation injury status, and % TBSA. Poisson regression was performed to estimate risk of in-hospital burn mortality.

resultsThere were a total of 7640 patients over the study period. The adjusted 60-day risk of in-hospital mortality in patients with preexisting renal disease (PRD was 3 times higher compared to patients with no preexisting renal disease (IRR = 3.22, 95% CI = 1.26-8.25). The adjusted 60-day risk of mortality is 2 times higher for patients with new onset renal disease compared to those without (IRR = 2.11, 95% CI = 1.55-2.87).

conclusionPreexisting and new onset renal disease results in a significantly higher risk of mortality following burn injury compared to patients without renal disease. Prevention of new onset renal injury and careful management of patients with preexisting renal disease to prevent exacerbation should be pursued.

Indexed as

AdultAgedBurnsBurn UnitsComorbidityFemaleHospitalizationHospital MortalityHumansIncidenceKidney DiseasesMaleMiddle AgedNorth CarolinaRetrospective StudiesRisk FactorsAcute kidney injuryBurn injuryBurn mortalityChronic renal diseaseRenal disease

Identifiers

PMID29526247
PMCPMC6855245

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.