Evidence map›Paper›PMID 29526012›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2018

Controlling Confinement and Topology to Study Collective Cell Behaviors.

Guillaume Duclos, Maxime Deforet, Hannah G Yevick, Olivier Cochet-Escartin, Flora Ascione, Sarah Moitrier, Trinish Sarkar, Victor Yashunsky, Isabelle Bonnet, Axel Buguin and 1 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Guillaume Duclos *Laboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France.
Maxime Deforet *Laboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France.
Hannah G Yevick *Laboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France.
Olivier Cochet-Escartin *Laboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France.
Flora AscioneLaboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France.
Sarah MoitrierLaboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France.
Trinish SarkarLaboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France.
Victor YashunskyLaboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France.
Isabelle BonnetLaboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France.
Axel BuguinLaboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France.
Pascal SilberzanLaboratoire PhysicoChimie Curie, Institut Curie, PSL Research University-Sorbonne Universités, UPMC-CNRS-Equipe labellisée Ligue Contre le Cancer, Paris, France. pascal.silberzan@curie.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Confinement and substrate topology strongly affect the behavior of cell populations and, in particular, their collective migration. In vitro experiments dealing with these aspects require strategies of surface patterning that remain effective over long times (typically several days) and ways to control the surface topology in three dimensions. Here, we describe protocols addressing these two aspects. High-resolution patterning of a robust cell-repellent coating is achieved by etching the coating through a photoresist mask patterned directly on the coated surface. Out-of-plane curvature can be controlled using glass wires or corrugated "wavy" surfaces.

Indexed as

AnimalsCell LineCell MovementHumansPolyethylene GlycolsPolyethylene GlycolsCollective cell migrationMicrofabricationNegative curvatureOut-of-plane curvaturePositive curvatureSurface patterning

Identifiers

PMID29526012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.