Evidence map›Paper›PMID 29525825›Full record

ArticlePflugers Archiv : European journal of physiology2018

Calcium mishandling impairs contraction in right ventricular hypertrophy prior to overt heart failure.

Amelia S Power, Anthony J Hickey, David J Crossman, Denis S Loiselle, Marie-Louise Ward

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  7. Cross-bridge thermodynamics in pulmonary arterial hypertensive right-ventricular failure.Journal of applied physiology (Bethesda, Md. : 1985) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amelia S PowerDepartment of Physiology, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1023, New Zealand.
Anthony J HickeySchool of Biological Sciences, University of Auckland, Private Bag 92019, Auckland, 1023, New Zealand.
David J CrossmanDepartment of Physiology, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1023, New Zealand.
Denis S LoiselleDepartment of Physiology, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1023, New Zealand.
Marie-Louise WardDepartment of Physiology, School of Medical Sciences, University of Auckland, Private Bag 92019, Auckland, 1023, New Zealand. m.ward@auckland.ac.nz.ORCID 0000-0002-3981-172X
University of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, there are no tailored therapies available for the treatment of right ventricular (RV) hypertrophy, and the cellular mechanisms that underlie the disease are poorly understood. We investigated the cellular changes that occur early in the progression of the disease, when RV hypertrophy is evident, but prior to the onset of heart failure. Intracellular Ca

Indexed as

AnimalsCalciumHeart FailureHeart VentriclesHypertension, PulmonaryHypertrophy, Right VentricularIsoproterenolMaleMonocrotalineMyocardial ContractionRatsRats, WistarSarcoplasmic ReticulumCalciumIsoproterenolMonocrotalineIntracellular calciumPulmonary hypertensionRight ventricular hypertrophyTransverse-tubulesβ-adrenergic stimulation

Identifiers

PMID29525825
OpenAlexW2790624029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.