ArticleJournal of the American Heart Association2018
Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 81 citations in OpenAlex.
- Hepatic triglyceride content does not affect circulating CETP: lessons from a liraglutide intervention trial and a population-based cohort.Scientific reports · 2019Trial
- High-density lipoprotein: a biomarker and therapeutic target in sepsis.Critical care (London, England) · 2025Review
- SUCNR1 Deficiency Alleviates Liver Ischemia-Reperfusion Injury by Regulating Kupffer Cell Activation and Polarization Through the ERK/NF-κB Pathway in Mice.Inflammation · 2025Article
- Kupffer cells abrogate homing and repopulation of allogeneic hepatic progenitors in injured liver site.Stem cell research & therapy · 2024Article
- Article
- Integrated omics analysis of coronary artery calcifications and myocardial infarction: the Framingham Heart Study.Scientific reports · 2023Article
- Immune and metabolic cross-links in the pathogenesis of comorbid non-alcoholic fatty liver disease.World journal of gastroenterology · 2023Review
- Impact of High-Density Lipoproteins on Sepsis.International journal of molecular sciences · 2022Review
- Modifiable Innate Biology within the Gut-Brain Axis for Alzheimer's Disease.Biomedicines · 2022Review
- Impact of gut microbiome on dyslipidemia in japanese adults: Assessment of the Shika-machi super preventive health examination results for causal inference.Frontiers in cellular and infection microbiology · 2022Article
- Heterogeneity and Function of Kupffer Cells in Liver Injury.Frontiers in immunology · 2022Review
- L. reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide.Journal of animal science and biotechnology · 2021Article
- Single-cell profiling reveals distinct immune phenotypes that contribute to ischaemia-reperfusion injury after steatotic liver transplantation.Cell proliferation · 2021Article
- Liver Injury and the Macrophage Issue: Molecular and Mechanistic Facts and Their Clinical Relevance.International journal of molecular sciences · 2021Review
- Bacterial lipopolysaccharide is associated with stroke.Scientific reports · 2021Article
- Article
- Development and Characterization of Nanobodies Targeting the Kupffer Cell.Frontiers in immunology · 2021Article
- Mechanism of TGF-β1 inhibiting Kupffer cell immune responses in cholestatic cirrhosis.Experimental and therapeutic medicine · 2020Article
- The lipid transfer properties of CETP define the concentration and composition of plasma lipoproteins.Journal of lipid research · 2020Article
- Contribution of Macrophage Efferocytosis to Liver Homeostasis and Disease.Frontiers in immunology · 2019Review
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLipopolysaccharide (LPS) decreases hepatic CETP (cholesteryl ester transfer protein) expression albeit that the underlying mechanism is disputed. We recently showed that plasma CETP is mainly derived from Kupffer cells (KCs). In this study, we investigated the role of KC subsets in the mechanism by which LPS reduces CETP expression. METHODS AND
resultsIn CETP-transgenic mice, LPS markedly decreased hepatic
conclusionsHepatic expression of CETP is exclusively confined to the resting KC subset (ie, F4/80
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Registered trials
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