ArticleAnnals of the rheumatic diseases2018
Determinants of psychological well-being in axial spondyloarthritis: an analysis based on linked claims and patient-reported survey data.
Article in Annals of the rheumatic diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Systematic Review of the Use of the WHO-5 Well-Being Index Across Different Disease Areas.Advances in therapy · 2025Pooled it
- The effects of WeChat-based educational intervention in patients with ankylosing spondylitis: a randomized controlled trail.Arthritis research & therapy · 2021Trial
- Supervised Group Exercise in Axial Spondyloarthritis: Patients' Satisfaction and Perspective on Evidence-Based Enhancements.Arthritis care & research · 2020Trial
- Depressive symptoms are associated with achieving remission in PsA patients - an analysis from the RABBIT-SpA register.BMC rheumatology · 2026Article
- Impact of Yoga on Spinal Mobility and Psychological Outcomes in Patients with Axial Spondyloarthritis: A Prospective Non-randomized Controlled Study.Rheumatology international · 2026Article
- Traditional Chinese Medicine (TCM) collaborative care involving acupuncture for axial spondyloarthritis: 6-week exploratory results of a pragmatic randomised controlled trial.EULAR rheumatology open · 2026Article
- Interrelations of disease activity, health-related quality of life, and mental health in axial spondyloarthritis: the Rheuma-VOR cohort.Frontiers in medicine · 2026Article
- How Do Fear-Avoidance and Catastrophizing Pain Beliefs Affect Functional Status and Disease Activity in Axial Spondyloarthritis?Medicina (Kaunas, Lithuania) · 2025Observational
- Associations between comorbidities and patient-reported outcomes in axial spondyloarthritis: data from a single-center real-world cohort.Clinical rheumatology · 2025Article
- Effect of depressive symptoms on treatment response in patients with axSpA: data from the RABBIT-SpA register.RMD open · 2025Observational
- COping with Rheumatic Stressors (CORS) questionnaire: validated German translation and cross-cultural adaptation for patients with axSpA.Journal of patient-reported outcomes · 2025Article
- Psychosocial burden of axial spondyloarthritis and impact of different disease domains: a systematic literature review.Rheumatology advances in practice · 2025Review
- Canadian Patients With Axial Spondyloarthritis Require Almost a Decade To Be Diagnosed Leading to Severe Functional Limitation. Results From the International Map of Axial Spondyloarthritis (IMAS).Musculoskeletal care · 2024Article
- Article
- A qualitative exploration of the patient journey in axial spondyloarthritis towards a people-centered understanding.Scientific reports · 2024Article
- Regional Differences in Diagnosis Journey and Healthcare Utilization: Results from the International Map of Axial Spondyloarthritis (IMAS).Rheumatology and therapy · 2024Article
- Disease activity and widespread pain are main contributors to patient-reported global health in axial spondyloarthritis: an analysis of 6064 patients.Rheumatology international · 2024Article
- Article
- Trends in health care of patients with vasculitides, including giant cell arteritis, Takayasu arteritis, ANCA-associated vasculitis and Behçet's disease: cross-sectional data of the German National Database 2007-2021.Rheumatology international · 2024Article
- Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to assess the psychological well-being and to analyse factors associated with depressive symptoms in axial spondyloarthritis (axSpA).
methodsA stratified random sample of subjects with a diagnosis of axSpA (International Classification of Diseases, Tenth Revision, German Modification M45) was drawn from health insurance data in Germany. These persons received a postal questionnaire on disease-related, psychological and lifestyle factors as well as socioeconomic status. Additional information to verify the axSpA diagnosis was also collected. The psychological well-being was assessed by means of the 5-item WHO Well-Being Index (WHO-5), which is considered a screening tool for depression. The following established cut-offs on the WHO-5 were applied: >50: good well-being, no depressive symptoms; 29-50: mild depressive symptoms; ≤28: moderate-to-severe depressive symptoms. Information on comorbidities, drug prescriptions and non-pharmacological treatment was retrieved from claims data and linked to the questionnaire data.
resultsA total of 1736 persons with a confirmed axSpA diagnosis were included. Using the cut-offs on the WHO-5, 533 persons (31%) were found to have moderate-to-severe depressive symptoms, 479 (28%) had mild depressive symptoms and 724 (42%) had a good well-being. Multivariable logistic regression revealed that higher disease activity, higher level of functional impairment, lower income, self-reported stress and lack of exercise, and younger age represent factors associated with moderate-to-severe depressive symptoms.
conclusionsThe prevalence of depressive symptoms in axSpA subjects is high and associated with disease-related parameters, socioeconomic status and lifestyle factors. These findings highlight the need for the careful evaluation of depressive symptoms as a part of the management strategy for axSpA.
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