Evidence map›Paper›PMID 29525760›Full record

ArticleBMJ case reports2018

Pancytopenia: a rare complication of Graves' disease.

Vishnu Vardhan Garla, Sohail Abdul Salim, Licy L Yanes-Cardozo

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Pre-treatment Neutropenia in Children and Adolescents with Autoimmune HyperthyroidismJournal of clinical research in pediatric endocrinology · 2021
    Article
  5. Article
  6. Graves' Disease with Pancytopenia and Hepatic Dysfunction: A Rare Case Presentation.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vishnu Vardhan GarlaInternal Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Sohail Abdul SalimInternal Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Licy L Yanes-CardozoInternal Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
University of Mississippi Medical Center · US

Funding

Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Pier Paolo Claudio, Babbette LaMarca · 2017 to 2026
$26.4M
Gender and susceptibility to kidney damage in high BP.R01HL069194 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI RECKELHOFF, JANE F · 2001 to 2010
$2.5M
NHLBI NIH HHS R01 HL069194NIGMS NIH HHS P20 GM121334
6 · The paper itself

Abstract

A 27-year-old male patient who presented to the emergency room with complaints of sweating, palpitations, heat intolerance, insomnia and weight loss for the last 3 months. His medical history was significant for hypertension. On examination, he was tachycardic, hypertensive, had tremors of the upper extremities and a smooth goitre with a thyroid bruit. Laboratory assessment revealed a suppressed thyroid-stimulating hormone, high free thyroxine and positive thyroid receptor antibodies. Complete blood count showed pancytopenia. As part of the work-up for pancytopenia, haptoglobin, ferritin, Coombs test, reticulocyte count hepatitis B and C antibodies were done, all of which were normal. Patient was started on methimazole, propranolol and hydrocortisone. His symptoms improved through the hospital course and he was subsequently discharged. Thyroidectomy was done once the patient's hyperthyroidism was controlled. Levothyroxine was started for the control of postsurgical hypothyroidism. Six months after thyroidectomy, the patient was euthyroid and the pancytopenia resolved.

Indexed as

AdultAntithyroid AgentsGraves DiseaseHumansImmunoglobulins, Thyroid-StimulatingMaleMethimazolePancytopeniaThyroidectomyThyrotropinThyroxineTreatment OutcomeAntithyroid AgentsImmunoglobulins, Thyroid-StimulatingMethimazoleThyrotropinThyroxinemalignant and benign haematologythyroid disease

Identifiers

PMID29525760
PMCPMC5847973
OpenAlexW2792245539

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.