ArticlePsychosomatics
Physical Symptom Burden and Its Association With Distress, Anxiety, and Depression in Breast Cancer.
Article in Psychosomatics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Prevalence of depression among breast cancer patients in Asia: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Cocreated internet-based stepped care for individuals with cancer and concurrent symptoms of anxiety and depression: Results from the U-CARE AdultCan randomized controlled trial.Psycho-oncology · 2020Trial
- A Qualitative Study of Family Centrality in Modified Dignity Therapy Experiences Among Korean Patients With Advanced Cancer: KCSG-PC22-10.Journal of Korean medical science · 2026Article
- Nursing Interventions for Symptom Management in Breast Cancer: A Systematic Review.International journal of women's health · 2026Review
- The Relationship Between Symptom Burden and Death Anxiety in Ovarian Cancer Patients: The Mediating Effect of Alexithymia.Journal of multidisciplinary healthcare · 2026Article
- Transcutaneous vagus nerve stimulation in breast cancer: a neuroimmune model to improve quality of life.Frontiers in oncology · 2026Article
- Nutritional vulnerability, food insecurity, and unmet supportive care needs in multiple myeloma: a cross-sectional study from China.Frontiers in nutrition · 2026Article
- Network analysis used to investigate the interplay among somatic and psychological symptoms in patients with cancer and cancer survivors: a scoping review.Journal of cancer survivorship : research and practice · 2025Article
- Detection of differences in physical symptoms between depressed and undepressed patients with breast cancer: a study using K-medoids clustering.BMC cancer · 2025Article
- Identifying Factors Associated With Heightened Anxiety During Breast Cancer Diagnosis Through the Analysis of Social Media Data on Reddit: Mixed Methods Study.JMIR cancer · 2024Article
- Prevalence and Correlates of Depressive Symptoms among Patients with Cancer: A Cross-Sectional Study.Current oncology (Toronto, Ont.) · 2024Article
- The Effectiveness of Nonpharmacological Interventions in the Management of Chemotherapy Physical Side Effects: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- Effects of nonpharmacological interventions on symptom clusters in breast cancer survivors: A systematic review of randomized controlled trials.Asia-Pacific journal of oncology nursing · 2024Review
- Depression and associated factors among adult breast cancer patients attending at selected public hospital in Addis Ababa, Ethiopia.SAGE open medicine · 2024Article
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- Distress Disorder Histories Relate to Greater Physical Symptoms Among Breast Cancer Patients and Survivors: Findings Across the Cancer Trajectory.International journal of behavioral medicine · 2023Article
- SymptomGraph: Identifying Symptom Clusters from Narrative Clinical Notes using Graph Clustering.Proceedings of the ... Symposium on Applied Computing. Symposium on Applied Computing · 2023Article
- The process of reaching psychological adjustment among adult women diagnosed with metastatic breast cancer and receiving cancer pharmacotherapy.Asia-Pacific journal of oncology nursing · 2023Article
- Race Differences in Patient-Reported Symptoms during Chemotherapy among Women with Early-Stage Hormone Receptor-Positive Breast Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Observational
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPhysical symptom burden and psychologic symptoms are highly prevalent in women with breast cancer. The Distress Thermometer and Problem List (DT&PL) is commonly used in oncology clinics to screen for distress and its accompanying Physical Problem List (PPL) identifies pertinent physical symptoms.
objectiveWe sought to identify physical symptoms found on the PPL and evaluate whether they are associated with psychologic symptoms in women with breast cancer.
methodsPatients (n=125) with breast cancer (Stage 0-IV) completed the DT&PL and the Hospital Anxiety and Depression Scale. They reported bother from any of 22 PPL items on the DT&PL. PPL items were assessed for their associations with distress, Hospital Anxiety and Depression Scale-anxiety, and Hospital Anxiety and Depression Scale-depression. The total number of PPL items endorsed per patient was evaluated for associations with psychologic outcomes, controlling for relevant demographic factors.
resultsMost physical problems were associated with depression (n = 13, 87%), and anxiety (n = 8, 53%), but fewer were associated with distress (n = 4, 27%). In multivariate analyses, a higher total number of problems was associated with younger age (p = 0.03) and more depressive symptoms (p < 0.001).
conclusionPhysical symptom burden detected by the DT&PL co-occurs with depression most commonly and to a lesser extent anxiety and distress in women with breast cancer. Depression is associated with more types of physical symptoms and a total number of physical symptoms. The endorsement of multiple PPL items on the DT&PL should prompt an evaluation for depression. Similarly, depression should prompt the evaluation and treatment of physical symptom burden.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.