Evidence map›Paper›PMID 29525250›Full record

ArticleJournal of the American Society of Echocardiography : official publication of the American Society of Echocardiography2018

Right Ventricular Longitudinal Strain Reproducibility Using Vendor-Dependent and Vendor-Independent Software.

Zachary J Il'Giovine, Hillary Mulder, Karen Chiswell, Kristine Arges, Jennifer Tomfohr, Abraham Hashmi, Eric J Velazquez, Joseph A Kisslo, Zainab Samad, Sudarshan Rajagopal

Abstract read
In one paragraph

Article in Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zachary J Il'GiovineInternal Medicine, Department of Medicine, Duke University, Durham, North Carolina.
Hillary MulderDuke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.
Karen ChiswellDuke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.
Kristine ArgesDivision of Cardiology, Department of Medicine, Duke University, Durham, North Carolina.
Jennifer TomfohrDivision of Cardiology, Department of Medicine, Duke University, Durham, North Carolina.
Abraham HashmiDepartment of Medicine, Aga Khan University, Karachi, Pakistan.
Eric J VelazquezDuke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina; Division of Cardiology, Department of Medicine, Duke University, Durham, North Carolina.
Joseph A KissloDivision of Cardiology, Department of Medicine, Duke University, Durham, North Carolina.
Zainab SamadDivision of Cardiology, Department of Medicine, Duke University, Durham, North Carolina.
Sudarshan RajagopalDivision of Cardiology, Department of Medicine, Duke University, Durham, North Carolina. Electronic address: sudarshan.rajagopal@dm.duke.edu.

Funding

Heart Failure Clinical Research Network Coordinating CenterU10HL084904 · NHLBI · DUKE UNIVERSITY · PI ANSTROM, KEVIN J, HERNANDEZ, ADRIAN · 2012 to 2018
$38.0M
STICHESR01HL105853 · NHLBI · DUKE UNIVERSITY · PI AL-KHALIDI, HUSSEIN · 2011 to 2015
$10.2M
TRANSFORM-HF CCCU01HL125511 · NHLBI · YALE UNIVERSITY · PI MENTZ, ROBERT JOHN, VELAZQUEZ, ERIC J · 2017 to 2021
$7.7M
Biomarkers of Mental Stress Induced Myocardial Ischemia and CHD PrognosisR01HL118077 · NHLBI · DUKE UNIVERSITY · PI JIANG, WEI · 2014 to 2016
$1.9M
Noncanonical Receptor Signaling in Pulmonary Arterial HypertensionK08HL114643 · NHLBI · DUKE UNIVERSITY · PI RAJAGOPAL, SUDARSHAN K · 2013 to 2017
$607k
NHLBI NIH HHS K08 HL114643NHLBI NIH HHS R01 HL105853NHLBI NIH HHS R01 HL118077NHLBI NIH HHS U01 HL125511NHLBI NIH HHS U10 HL084904
6 · The paper itself

Abstract

backgroundRight ventricular peak systolic longitudinal strain (RVLS) has emerged as an approach for quantifying right ventricular function in diseases such as pulmonary hypertension and congenital heart disease. A major limitation in applying RVLS is that strain imaging and analysis are proprietary, which may result in systematic differences from vendor to vendor. The goal of this study was to test the reproducibility of right ventricular strain analysis among selected vendor-specific software (VSS) and vendor-independent software (VIS) on images obtained from different ultrasound scanners, as would be common in clinical practice or in a multicenter clinical trial.

methodsIn this prospective, single-center study, 35 patients (5 healthy subjects and 30 with pulmonary hypertension) each underwent two echocardiographic scans, one using GE (Vivid E9) and the other using Philips (iE33) ultrasound systems. Images were analyzed using both VSS and VIS (TomTec) software for determination of RVLS. A repeated-measures analysis of variance was used to assess for any systematic differences among methods, as well as effects of scanner and software and a possible interaction between scanner and software for each strain measurement.

resultsDifferences for global strains were not statistically significant among VSS packages (P ≥ .05), but some differences were noted between VSS and VIS. Wide variability between regional peak strain measurements was noted, but no systematic differences were found.

conclusionsGlobal RVLS values between VSS systems are not significantly different but may differ slightly from VIS. When comparing regional strain between VSS and VIS analyses, there is widespread variability without clear systematic differences.

Indexed as

SoftwareAdultAgedEchocardiographyFemaleFollow-Up StudiesHeart VentriclesHumansHypertension, PulmonaryImage Interpretation, Computer-AssistedMaleMiddle AgedProspective StudiesReproducibility of ResultsVentricular Function, RightEchocardiographyReproducibilityRight ventricular strainValidation

Identifiers

PMID29525250
PMCPMC6825401

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.