Evidence map›Paper›PMID 29524848›Full record

ReviewCurrent opinion in neurobiology2018

Neurocircuitry of aggression and aggression seeking behavior: nose poking into brain circuitry controlling aggression.

Hossein Aleyasin, Meghan E Flanigan, Scott J Russo

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
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  8. Rethinking Norm Psychology.Perspectives on psychological science : a journal of the Association for Psychological Science · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. On Associations between Fear-Induced Aggression,International journal of molecular sciences · 2023
    Article
  14. Article
  15. Article
  16. The Genetic and Neural Substrates of Externalizing Behavior.Biological psychiatry global open science · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hossein AleyasinFishberg Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Meghan E FlaniganFishberg Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Scott J RussoFishberg Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States. Electronic address: scott.russo@mssm.edu.

Funding

REPRESSIVE HISTONE AND DNA METHYLATION IN RODENT DEPRESSION MODELSP50MH096890 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ALLIS, CHARLES DAVID · 2012 to 2021
$20.2M
Pasinetti: Project 3; Role of Microbiome in Promotion of Cognitive and Psychological Resilience (Faith)P50AT008661 · NCCIH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUSSO, SCOTT JAMES · 2015 to 2019
$11.2M
Role of thalamic versus cortical inputs to nucleus accumbens in stress-related disordersR01MH090264 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUSSO, SCOTT JAMES · 2011 to 2020
$4.2M
Role of lateral habenula orexin receptor signaling in aggressive social behaviorR01MH114882 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUSSO, SCOTT JAMES · 2017 to 2021
$2.7M
Lateral Habenula Orexin Receptor 2 Regulation of Aggression RewardF31MH111108 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FLANIGAN, MEGHAN ELIZABETH · 2017 to 2018
$78k
NCCIH NIH HHS P50 AT008661NIMH NIH HHS F31 MH111108NIMH NIH HHS P50 MH096890NIMH NIH HHS R01 MH090264NIMH NIH HHS R01 MH114882
6 · The paper itself

Abstract

Aggression is an innate behavior that helps individuals succeed in environments with limited resources. Over the past few decades, neurobiologists have identified neural circuits that promote and modulate aggression; however, far less is known regarding the motivational processes that drive aggression. Recent research suggests that aggression can activate reward centers in the brain to promote positive valence. Here, we review major recent findings regarding neural circuits that regulate aggression, with an emphasis on those regions involved in the rewarding or reinforcing properties of aggressive behavior.

Indexed as

MotivationNoseRewardAggressionAnimalsBrainHumansNeural Pathways

Identifiers

PMID29524848
PMCPMC5935264

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.