Evidence map›Paper›PMID 29524059›Full record

ArticleEcoHealth2018

Vaccination Against Porcine Circovirus-2 Reduces Severity of Tuberculosis in Wild Boar.

David Risco, María Bravo, Remigio Martínez, Almudena Torres, Pilar Gonçalves, Jesús Cuesta, Waldo García-Jiménez, Rosario Cerrato, Rocío Iglesias, Javier Galapero and 4 more

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In one paragraph

Article in EcoHealth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

David RiscoInnovación en Gestión y Conservación de Ungulados S.L., Calle San Pedro de Alcántara nº 12 Portal 5 5ºR, Cáceres, Spain. driscope@gmail.com.ORCID http://orcid.org/0000-0003-3405-8801
María BravoInnovación en Gestión y Conservación de Ungulados S.L., Calle San Pedro de Alcántara nº 12 Portal 5 5ºR, Cáceres, Spain.
Remigio MartínezDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Almudena TorresDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Pilar GonçalvesInnovación en Gestión y Conservación de Ungulados S.L., Calle San Pedro de Alcántara nº 12 Portal 5 5ºR, Cáceres, Spain.
Jesús CuestaDepartamento de Medicina Animal, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Waldo García-JiménezDepartment of Pathology and Infectious Diseases, Faculty of Health and Medical Sciences, School of Veterinary Medicine, University of Surrey, Guildford, Surrey, UK.
Rosario CerratoInnovación en Gestión y Conservación de Ungulados S.L., Calle San Pedro de Alcántara nº 12 Portal 5 5ºR, Cáceres, Spain.
Rocío IglesiasDepartamento de Bioquímica y Biología Molecular y Genética, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Javier GalaperoDepartamento de Medicina Animal, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Emmanuel SerranoWildlife Ecology & Health group and Servei d'Ecopatologia de Fauna Salvatge (SEFaS), Departament de Medicina i Cirurgia Animals Facultat de Veterinària, Universitat Autònoma de Barcelona (UAB) E-08193, Bellaterra, Barcelona, Spain.
Luis GómezDepartamento de Medicina Animal, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Pedro Fernández-LlarioInnovación en Gestión y Conservación de Ungulados S.L., Calle San Pedro de Alcántara nº 12 Portal 5 5ºR, Cáceres, Spain.
Javier Hermoso de MendozaDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Extremadura, Cáceres, Spain.
Universidad de Extremadura · ESHospital San Pedro de Alcántara · ESUniversitat Autònoma de Barcelona · ESUniversity of Surrey · GB

Funding

Gobierno de Extremadura PO14024Secretaría de Estado de Investigación, Desarrollo e Innovación PTQ14-06663Secretaría de Estado de Investigación, Desarrollo e Innovación RYC-2016-21120
6 · The paper itself

Abstract

Tuberculosis (TB) in wild boar (Sus scrofa) may be affected by coinfections with other pathogens, such as porcine circovirus type 2 (PCV2). Therefore, sanitary measures focused on controlling PCV2 could be useful in reducing the impact of TB in this wild suid. The aim of this study was to explore whether vaccination against PCV2 targeting young animals affects TB prevalence and TB severity in wild boar. The study was conducted on a game estate in mid-western Spain. Seventy animals of ages ranging from 4 to 8 months were captured, individually identified, vaccinated against PCV2 and released, forming a vaccinated group. Not-captured animals cohabiting with the vaccinated wild boar constituted the control group. Animals from both groups were hunted between 2013 and 2016 and a TB diagnosis based on pathological assessment and microbiological culture was made in all of them. The effect of PCV2 vaccination on TB prevalence and severity was explored using generalized lineal models. Whereas TB prevalence was similar in vaccinated and control groups (54.55 vs. 57.78%), vaccinated animals showed less probabilities to develop generalized TB lesions. Furthermore, mean TB severity score was significantly lower in vaccinated animals (1.55 vs. 2.42) suggesting a positive effect of PCV2 vaccination.

Indexed as

AnimalsAnimals, WildCircoviridae InfectionsCircovirusCoinfectionSeverity of Illness IndexSpainSus scrofaSwineSwine DiseasesTuberculosisVaccinationViral VaccinesViral VaccinesPCV2TuberculosisVaccinationWild boar

Identifiers

PMID29524059
OpenAlexW2791431212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.