ArticleArchives of toxicology2018
Acute exposure to diesel exhaust impairs adult neurogenesis in mice: prominence in males and protective effect of pioglitazone.
Article in Archives of toxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 53 citations in OpenAlex.
- Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Impact of Continuously Improved Air Quality on Mental Health: A Quasi-experimental Study Based on Longitudinal Observations for Chinese Adults.Environment & health (Washington, D.C.) · 2025Article
- The Effects of Air Pollution on Neurological Diseases: A Narrative Review on Causes and Mechanisms.Toxics · 2025Review
- Multiphase Radical Chemical Processes Induced by Air Pollutants and the Associated Health Effects.Environment & health (Washington, D.C.) · 2025Review
- Article
- Air Pollution-Related Neurotoxicity Across the Life Span.Annual review of pharmacology and toxicology · 2023Review
- Association between short-term air pollution exposure and traumatic intracranial hemorrhage: pilot evidence from Taiwan.Frontiers in neurology · 2023Article
- Air Pollution: Possible Interaction between the Immune and Nervous System?International journal of environmental research and public health · 2022Review
- Association between air pollution and CSF sTREM2 in cognitively normal older adults: The CABLE study.Annals of clinical and translational neurology · 2022Article
- Genomic Basis for Individual Differences in Susceptibility to the Neurotoxic Effects of Diesel Exhaust.International journal of molecular sciences · 2022Article
- Microglial Activation and Oxidative Stress in PMAntioxidants (Basel, Switzerland) · 2022Review
- Recently decreased association of air pollution with cognitive impairment in a population-based aging cohort and in a mouse model.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- Particulate matter pollution associated with schizophrenia hospital re-admissions: a time-series study in a coastal Chinese city.Environmental science and pollution research international · 2021Article
- Cerebral cortex and blood transcriptome changes in mouse neonates prenatally exposed to air pollution particulate matter.Journal of neurodevelopmental disorders · 2021Article
- Effects of air pollution exposure on social behavior: a synthesis and call for research.Environmental health : a global access science source · 2021Review
- The Effects of Chronic Exposure to Ambient Traffic-Related Air Pollution on Alzheimer's Disease Phenotypes in Wildtype and Genetically Predisposed Male and Female Rats.Environmental health perspectives · 2021Article
- Neurovascular Alterations in Vascular Dementia: Emphasis on Risk Factors.Frontiers in aging neuroscience · 2021Article
- Developmental exposure to diesel exhaust upregulates transcription factor expression, decreases hippocampal neurogenesis, and alters cortical lamina organization: relevance to neurodevelopmental disorders.Journal of neurodevelopmental disorders · 2020Article
- Genomic approach to explore altered signaling networks of olfaction in response to diesel exhaust particles in mice.Scientific reports · 2020Article
- Adult mouse hippocampal transcriptome changes associated with long-term behavioral and metabolic effects of gestational air pollution toxicity.Translational psychiatry · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Adult neurogenesis is the process by which neural stem cells give rise to new functional neurons in specific regions of the adult brain, a process that occurs throughout life. Significantly, neurodegenerative and psychiatric disorders present suppressed neurogenesis, activated microglia, and neuroinflammation. Traffic-related air pollution has been shown to adversely affect the central nervous system. As the cardinal effects of air pollution exposure are microglial activation, and ensuing oxidative stress and neuroinflammation, we investigated whether acute exposures to diesel exhaust (DE) would inhibit adult neurogenesis in mice. Mice were exposed for 6 h to DE at a PM
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.