Evidence map›Paper›PMID 29523910›Full record

ArticleCurrent microbiology2018

Tracking Multidrug-Resistant Klebsiella pneumoniae from an Italian Hospital: Molecular Epidemiology and Surveillance by PFGE, RAPD and PCR-Based Resistance Genes Prevalence.

Giancarlo Ripabelli, Manuela Tamburro, Giuliana Guerrizio, Incoronata Fanelli, Romeo Flocco, Massimiliano Scutellà, Michela L Sammarco

Abstract read
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In one paragraph

Article in Current microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Molecular typing of clinical and environmental isolates ofIranian journal of basic medical sciences · 2022
    Article
  11. Polyclonal Endemicity of Carbapenemase-ProducingAntibiotics (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
  14. Prevalence and Antimicrobial Resistance ofAntibiotics (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Molecular Characterization of Carbapenemase-ProducingInfection and drug resistance · 2021
    Article
  17. Biofilm Production by Carbapenem-ResistantFrontiers in cellular and infection microbiology · 2020
    Article
  18. Review
  19. Prevalence and Distribution Characteristics ofInfection and drug resistance · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giancarlo RipabelliDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via De Sanctis, 86100, Campobasso, Italy. ripab@unimol.it.
Manuela TamburroDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via De Sanctis, 86100, Campobasso, Italy.
Giuliana GuerrizioDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via De Sanctis, 86100, Campobasso, Italy.
Incoronata FanelliDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via De Sanctis, 86100, Campobasso, Italy.
Romeo FloccoAnesthesia and Resuscitation Unit of "Antonio Cardarelli" Hospital, Azienda Sanitaria Regionale Molise, Campobasso, Italy.
Massimiliano ScutellàLaboratory Medicine Unit of "Antonio Cardarelli" Hospital, Azienda Sanitaria Regionale Molise, Campobasso, Italy.
Michela L SammarcoDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via De Sanctis, 86100, Campobasso, Italy.
University of Molise · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial-resistant Klebsiella pneumoniae represent a global public health concern. K. pneumoniae strains isolated during 2010 and 2014-2016 within a single hospital of Molise Region, Central Italy, were analyzed testing antimicrobial susceptibility, clonality by pulsed-field gel electrophoresis (PFGE) and random amplified polymorphic DNA (RAPD)-PCR, and prevalence of carbapenem resistance genes by PCR. Forty isolates (23 wild-type in 2010 and 17 non-wild-type in 2014-2016) were collected from hospitalized patients (65.2 ± 18.1 years old, 75% male, 80% from intensive care unit-ICU). K. pneumoniae showed multidrug-resistant profiles and 15 resistotypes were identified (discriminatory power D = 0.88). The 69.6 and 17.4% of isolates in 2010 resulted intermediate and resistant to imipenem, respectively, and 91.3% was sensitive to meropenem, while 88.2% of isolates of 2014-2016 were resistant to both antibiotics. PFGE identified 16 clusters versus 23 by RAPD, 26 pulsotypes versus 33 RAPD patterns (D ≥ 0.97). PFGE separated strains according to isolation period and identified an outbreak occurred in the ICU during December 2014 and January 2015. No strains harbored bla

Indexed as

AdultAgedAged, 80 and overAnti-Bacterial Agentsbeta-LactamasesCarbapenemsDNA, BacterialDrug Resistance, Multiple, BacterialElectrophoresis, Gel, Pulsed-FieldFemaleHumansInfant, NewbornIntensive Care UnitsItalyKlebsiella InfectionsKlebsiella pneumoniaeAnti-Bacterial Agentsbeta-LactamasesCarbapenemsDNA, Bacterial

Identifiers

PMID29523910
OpenAlexW2790539584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.