ArticleScientific reports2018
Systematic Evaluation of Non-Uniform Sampling Parameters in the Targeted Analysis of Urine Metabolites by
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- The Evolving Landscape of NMR Structural Elucidation.Molecules (Basel, Switzerland) · 2026Review
- Simultaneous determination of free and total metabolite concentrations in proteinaceous specimens by 1DCell reports methods · 2026Article
- Applications of chromatographic methods in metabolomics: A review.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2024Review
- NMR methods for the analysis of mixtures.Chemical communications (Cambridge, England) · 2022Review
- NMR and Metabolomics-A Roadmap for the Future.Metabolites · 2022Review
- High fidelity sampling schedules for NMR spectra of high dynamic range.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2022Article
- Gadolinium-Based Paramagnetic Relaxation Enhancement Agent Enhances Sensitivity for NUS Multidimensional NMR-Based Metabolomics.Molecules (Basel, Switzerland) · 2021Article
- Chronic Kidney Disease Cohort Studies: A Guide to Metabolome Analyses.Metabolites · 2021Review
- AnMetabolites · 2021Article
- Development of an NMR-Based Platform for the Direct Structural Annotation of Complex Natural Products Mixtures.Journal of natural products · 2021Article
- Metabolic mechanisms of a drug revealed by distortion-freeChemical science · 2021Article
- Virtual decoupling to break the simplification versus resolution trade-off in nuclear magnetic resonance of complex metabolic mixtures.Magnetic resonance (Gottingen, Germany) · 2021Article
- Reducing the measurement time of exact NOEs by non-uniform sampling.Journal of biomolecular NMR · 2020Article
- Robust Metabolite Quantification from J-Compensated 2DMetabolites · 2020Article
- Quantitative NMR-Based Biomedical Metabolomics: Current Status and Applications.Molecules (Basel, Switzerland) · 2020Review
- Review
- Evaluation of Non-Uniform Sampling 2DMetabolites · 2020Article
- Article
- Real-Time Pure Shift HSQC NMR for Untargeted Metabolomics.Analytical chemistry · 2019Article
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Authors and funding
3 authors.
Funding
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Abstract
Non-uniform sampling (NUS) allows the accelerated acquisition of multidimensional NMR spectra. The aim of this contribution was the systematic evaluation of the impact of various quantitative NUS parameters on the accuracy and precision of 2D NMR measurements of urinary metabolites. Urine aliquots spiked with varying concentrations (15.6-500.0 µM) of tryptophan, tyrosine, glutamine, glutamic acid, lactic acid, and threonine, which can only be resolved fully by 2D NMR, were used to assess the influence of the sampling scheme, reconstruction algorithm, amount of omitted data points, and seed value on the quantitative performance of NUS in
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