Evidence map›Paper›PMID 29523657›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

15-epi-Lipoxin A

Ho Pan Sham, Katherine H Walker, Raja-Elie E Abdulnour, Nandini Krishnamoorthy, David N Douda, Paul C Norris, Ioanna Barkas, Sarah Benito-Figueroa, Jennifer K Colby, Charles N Serhan and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 75 citations in OpenAlex.

  1. Plasma Resolvin D2 to Leukotriene BBioMed research international · 2021
    Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Lipoxin AbioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Lipoxin alleviates oxidative stress: a state-of-the-art review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Ho Pan ShamPulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; and.
Katherine H WalkerPulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; and.ORCID 0000-0003-1198-8125
Raja-Elie E AbdulnourPulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; and.
Nandini KrishnamoorthyPulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; and.
David N DoudaPulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; and.
Paul C NorrisCenter for Experimental Therapeutics and Reperfusion Injury, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115.
Ioanna BarkasPulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; and.ORCID 0000-0003-4625-6207
Sarah Benito-FigueroaPulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; and.
Jennifer K ColbyPulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; and.
Charles N SerhanCenter for Experimental Therapeutics and Reperfusion Injury, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115.ORCID 0000-0003-4627-8545
Bruce D LevyPulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; and blevy@bwh.harvard.edu.
Brigham and Women's Hospital · US

Funding

RESPIRATORY RESEARCHT32HL007633 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI George R Washko · 1985 to 2026
$14.9M
Resolution Mechanisms in Acute Inflammation: Resolution PharmacologyP01GM095467 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI PETASIS, NICOS A · 2011 to 2020
$14.8M
Specialized Pro-Resolving Mediators in AsthmaR01HL122531 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LEVY, BRUCE D · 2014 to 2024
$4.7M
Role of maresin 1 in the resolution of lung inflammationK08HL130540 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDULNOUR, RAJA-ELIE EDWARD · 2016 to 2019
$691k
Specialized Pro-Resolving Mediators in the Resolution of Respiratory Viral InfectionF32AI134019 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI WALKER, KATHERINE · 2017 to 2018
$140k
NHLBI NIH HHS K08 HL130540NHLBI NIH HHS R01 HL122531NHLBI NIH HHS T32 HL007633NIAID NIH HHS F32 AI134019NIGMS NIH HHS P01 GM095467
6 · The paper itself

Abstract

Specialized proresolving mediators (SPMs) decrease NF-κB activity to prevent excessive tissue damage and promote the resolution of acute inflammation. Mechanisms for NF-κB regulation by SPMs remain to be determined. In this study, after LPS challenge, the SPMs 15-epi-lipoxin A

Indexed as

AnimalsCell LineDocosahexaenoic AcidsFatty Acids, UnsaturatedHumansInflammationInflammation MediatorsLipoxinsMaleMiceMice, Inbred C57BLMice, KnockoutNF-kappa BPneumonia, BacterialReceptors, Interleukin-1Tumor Necrosis Factor alpha-Induced Protein 3Docosahexaenoic AcidsFatty Acids, UnsaturatedInflammation Mediatorslipoxin A4LipoxinsNF-kappa BReceptors, Interleukin-1resolvin D2resolvin D3Tumor Necrosis Factor alpha-Induced Protein 3

Identifiers

PMID29523657
PMCPMC5906795
OpenAlexW2791017891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.