Evidence map›Paper›PMID 29523629›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2018

Yusuf Menda, Mark T Madsen, Thomas M O'Dorisio, John J Sunderland, G Leonard Watkins, Joseph S Dillon, Sarah L Mott, Michael K Schultz, Gideon K D Zamba, David L Bushnell and 1 more

Registry-linked trialOpen access · bronzeAbstract readClinical Trial, Phase II
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03923257 (Phase I Trial of Peptide Receptor Radiotherapy), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03923257 phase1 / phase2withdrawnnot on this mapstarted 2020, after this paper: background citation

Phase I Trial of Peptide Receptor Radiotherapy (PRRT) With 177Lu-DOTA-tyr3-Octreotate (177Lu-DOTATATE) in Children and Adolescents With Neuroendocrine Tumor or Pheochromocytoma/Paraganglioma

TypeinterventionalSponsorSue O'DorisioRan2020 to 2021Enrolled0ConditionsNeuroendocrine Tumors, Pheochromocytoma, ParagangliomaArms177Lu-DOTA-tyr3-OCTREOTATE, Peptide Receptor Radiotherapy (PRRT)
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
  2. Review
  3. Molecular radiotherapy for adult type metastatic neuroendocrine tumours in children.European journal of nuclear medicine and molecular imaging · 2025
    Observational
  4. Article
  5. Review
  6. Survival impact of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  7. The University of Iowa Neuroendocrine Tumor Clinic.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Use of imaging-based dosimetry for personalising radiopharmaceutical therapy of cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
    Review
  12. Article
  13. Review
  14. Review
  15. Addition ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  16. Review
  17. Feasibility of Single-Time-Point Dosimetry for Radiopharmaceutical Therapies.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  18. Theragnostic Aspects and Radioimmunotherapy in Pediatric Tumors.International journal of molecular sciences · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yusuf MendaDepartment of Radiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa yusuf-menda@uiowa.edu.
Mark T MadsenDepartment of Radiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Thomas M O'DorisioDepartment of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
John J SunderlandDepartment of Radiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
G Leonard WatkinsDepartment of Radiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Joseph S DillonDepartment of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Sarah L MottHolden Comprehensive Cancer Center, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Michael K SchultzDepartment of Radiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Gideon K D ZambaDepartment of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa; and.
David L BushnellDepartment of Radiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
M Sue O'DorisioDepartment of Pediatrics, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
University of Iowa · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
Project 4: New Approaches to Improving the Effectiveness of Radionuclide Targeted Treatments in Neuroendocrine TumorsP50CA174521 · NCI · UNIVERSITY OF IOWA · PI ODORISIO, THOMAS · 2015 to 2021
$13.2M
Image-guided Diagnosis and Therapy of Neuroendocrine TumorsR01CA167632 · NCI · UNIVERSITY OF IOWA · PI MENDA, YUSUF, O'DORISIO, M. SUE · 2012 to 2016
$2.6M
NCI NIH HHS P50 CA174521NCI NIH HHS R01 CA167632
6 · The paper itself

Abstract

Pretherapy PET with

Indexed as

AdolescentAdultAgedBone MarrowFemaleHumansKidneyMaleMiddle AgedNeuroendocrine TumorsOctreotidePositron Emission Tomography Computed TomographyPrecision MedicineProspective StudiesRadiopharmaceuticalsRadiotherapy Dosage90Y-octreotide, DOTA-Tyr(3)-OctreotideRadiopharmaceuticalsReceptors, SomatostatinYttrium Radioisotopes90Y-DOTATOCdosimetryneuroendocrinepeptide receptor radiotherapyradiobiology/dosimetryradionuclide therapy

Identifiers

PMID29523629
PMCPMC6225542
OpenAlexW2790509779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.