Evidence map›Paper›PMID 29523553›Full record

ArticleApplied and environmental microbiology2018

Estrogen Degraders and Estrogen Degradation Pathway Identified in an Activated Sludge.

Yi-Lung Chen, Han-Yi Fu, Tzong-Huei Lee, Chao-Jen Shih, Lina Huang, Yu-Sheng Wang, Wael Ismail, Yin-Ru Chiang

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 78 citations in OpenAlex.

  1. Catabolic Mechanism of 17β-Estradiol inJournal of microbiology and biotechnology · 2026
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  12. Microorganisms · 2022
    Article
  13. Biodegradation and Metabolic Pathway of 17β-Estradiol byInternational journal of molecular sciences · 2022
    Article
  14. Temporal compositional shifts in an activated sludge microbiome during estrone biodegradation.Environmental science and pollution research international · 2022
    Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Yi-Lung ChenBiodiversity Research Center, Academia Sinica, Taipei, Taiwan.
Han-Yi FuBiodiversity Research Center, Academia Sinica, Taipei, Taiwan.
Tzong-Huei LeeInstitute of Fisheries Science, National Taiwan University, Taipei, Taiwan.
Chao-Jen ShihBioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu, Taiwan.
Lina HuangBioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu, Taiwan.
Yu-Sheng WangBiodiversity Research Center, Academia Sinica, Taipei, Taiwan.
Wael IsmailEnvironmental Biotechnology Program, Life Sciences Department, College of Graduate Studies, Arabian Gulf University, Manama, Bahrain.
Yin-Ru ChiangBiodiversity Research Center, Academia Sinica, Taipei, Taiwan yinru915@gate.sinica.edu.tw.
Biodiversity Research Center, Academia Sinica · TWFood Industry Research and Development Institute · TWArabian Gulf University · BHNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The environmental release and fate of estrogens are becoming an increasing public concern. Bacterial degradation has been considered the main process for eliminating estrogens from wastewater treatment plants. Various bacterial isolates are reportedly capable of aerobic estrogen degradation, and several estrogen degradation pathways have been proposed in proteobacteria and actinobacteria. However, the ecophysiological relevance of estrogen-degrading bacteria in the environment is unclear. In this study, we investigated the estrogen degradation pathway and corresponding degraders in activated sludge collected from the Dihua Sewage Treatment Plant, Taipei, Taiwan. Cultivation-dependent and cultivation-independent methods were used to assess estrogen biodegradation in the collected activated sludge. Estrogen metabolite profile analysis revealed the production of pyridinestrone acid and two A/B-ring cleavage products in activated sludge incubated with estrone (1 mM), which are characteristic of the 4,5-

Indexed as

Metabolic Networks and PathwaysBacteriaBacterial ProteinsBiodegradation, EnvironmentalEstrogensEstroneMetagenomicsPhylogenySewageTaiwanWastewaterWater Pollutants, ChemicalBacterial ProteinsEstrogensEstroneSewageWastewaterWater Pollutants, Chemicalactivated sludgebiodegradationestronemeta-cleavage dioxygenaseNovosphingobiumwastewater treatment plant

Identifiers

PMID29523553
PMCPMC5930366
OpenAlexW2789541819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.