Observational studyPediatric neurology2018
Antecedents of Screening Positive for Attention Deficit Hyperactivity Disorder in Ten-Year-Old Children Born Extremely Preterm.
Observational study in Pediatric neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Prenatal exposure to antibiotics and risk of neurodevelopmental disorders in offspring: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Antibiotic exposure and childhood attention-deficit/hyperactivity disorder: systematic review and meta-analysis.Psychopharmacology · 2021Pooled it
- Maternal Hypertensive Pregnancy Disorders and Mental and Behavioral Disorders in the Offspring: a Review.Current hypertension reports · 2021Pooled it
- Health-related quality of life at age 10 years in children born extremely preterm.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Association of Pediatric Buccal Epigenetic Age Acceleration With Adverse Neonatal Brain Growth and Neurodevelopmental Outcomes Among Children Born Very Preterm With a Neonatal Infection.JAMA network open · 2022Article
- Extreme prematurity: Risk and resiliency.Current problems in pediatric and adolescent health care · 2022Review
- Association of prenatal modifiable risk factors with attention-deficit hyperactivity disorder outcomes at age 10 and 15 in an extremely low gestational age cohort.Frontiers in human neuroscience · 2022Article
- Development of the genomic inflammatory index (GII) to assess key maternal antecedents associated with placental inflammation.Placenta · 2021Article
- Placental programming, perinatal inflammation, and neurodevelopment impairment among those born extremely preterm.Pediatric research · 2021Review
- Microbial invasion of the amniotic cavity is associated with impaired cognitive and motor function at school age in preterm children.Pediatric research · 2020Article
- What Do We Know About the Preterm Behavioral Phenotype? A Narrative Review.Frontiers in psychiatry · 2020Review
- Psychiatric Symptoms: Prevalence, Co-occurrence, and Functioning Among Extremely Low Gestational Age Newborns at Age 10 Years.Journal of developmental and behavioral pediatrics : JDBP · 2019Observational
- Sex-Dependent Effects of Perinatal Inflammation on the Brain: Implication for Neuro-Psychiatric Disorders.International journal of molecular sciences · 2019Review
- Assessing Positive Child Health among Individuals Born Extremely Preterm.The Journal of pediatrics · 2018Article
- Neurologic Consequences of Preterm Birth.Current neurology and neuroscience reports · 2018Review
- Maternal obesity and attention-related symptoms in the preterm offspring.Early human development · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundThe incidence of attention deficit hyperactivity disorder is higher among children born very preterm than among children who are mature at birth.
methodsWe studied 583 ten-year-old children who were born before 28 weeks of gestation whose IQ was above 84 and had a parent-completed Child Symptom Inventory-4, which allowed classification of the child as having or not having symptoms of attention deficit hyperactivity disorder. For 422 children, we also had a teacher report, and for 583 children, we also had a parent report of whether or not a physician made an attention deficit hyperactivity disorder diagnosis.
resultsThe risk profile of screening positive for attention deficit hyperactivity disorder based on a parent's report differed from the risk profile based on the teacher's report, whereas the risk profile according to a physician and according to any two observers closely resembled the parent-reported profile. Among the statistically significant risk factors were young maternal age (parent, physician, and two observers), maternal obesity (parent, physician, and two observers), maternal smoking (parent, physician, and two observers), magnesium given at delivery for seizure prophylaxis (parent and two observers), recovery of Mycoplasma sp. from the placenta (teacher and two observers), low gestational age (parent and two observers), low birth weight (teacher and physician), singleton (parent, physician, and two observers), male (parent, teacher, physician, and two observers), mechanical ventilation on postnatal day seven (physician), receipt of a sedative (parent and two observers), retinopathy of prematurity (parent), necrotizing enterocolitis (physician), antibiotic receipt (physician and two observers), and ventriculomegaly on brain scan (parent and two observers).
conclusionsThe multiplicity of risk factors identified can be subsumed as components of four broad themes: low socioeconomic state, immaturity or vulnerability, inflammation, and epigenetic phenomena.
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Registered trials
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