ReviewAutonomic neuroscience : basic & clinical2018
Postural tachycardia syndrome - Diagnosis, physiology, and prognosis.
Review in Autonomic neuroscience : basic & clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 95 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Physical Exercise in Patients With Postural Orthostatic Tachycardia Syndrome (POTS) After Covid-19.
Effects of Individual Tailored Physical Exercise in Patients With Post COVID-19 Condition, Diagnosed With Postural Orthostatic Tachycardia Syndrome (POTS) - a Randomized Controlled Study
Who cites it
95 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic literature review: treatment of postural orthostatic tachycardia syndrome (POTS).Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Pooled it
- Faintly tired: a systematic review of fatigue in patients with orthostatic syncope.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Pooled it
- Abdominal-only Compression Garments Reduce Orthostatic Tachycardia and Improve Symptoms in Patients With Postural Orthostatic Tachycardia Syndrome.The Canadian journal of cardiology · 2026Trial
- Effect of High Dietary Sodium Intake in Patients With Postural Tachycardia Syndrome.Journal of the American College of Cardiology · 2021Trial
- Splanchnic Venous Compression Enhances the Effects of ß-Blockade in the Treatment of Postural Tachycardia Syndrome.Journal of the American Heart Association · 2020Trial
- Impact of COVID‑19 infection on subsequent prescriptions of autonomic dysfunction pharmacotherapy: a nationwide propensity‑score‑matched Cohort study in Japan.Annals of medicine · 2026Article
- Hyperadrenergic and neuropathic features based on clinical autonomic testing in individuals with POTS: an observational cross-sectional study.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Long-term outcomes in patients with postural orthostatic tachycardia syndrome with an average follow-up of over 20 years.Journal of internal medicine · 2026Article
- Plasma Cytokine and Caspase-1p20 Profiles in Pre-Pandemic and Long COVID-Associated Postural Orthostatic Tachycardia Syndrome.Biomedicines · 2026Article
- Current status and future perspectives on the mechanistic and pathophysiological understanding of long COVID.Communications medicine · 2026Article
- Post-Exertional Malaise in Post-COVID-19 Syndrome: A Shift in the Frequency Across Pandemic Phases.Journal of clinical medicine · 2026Article
- Hyperadrenergic postural tachycardia syndrome associated with augmented neurovascular transduction.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Hemodynamic and cerebral oxygenation predictors of visual darkening in pediatric POTS: a cross-sectional study.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Evanescent Hyperemia: An Underrecognized Cutaneous Manifestation of Postural Orthostatic Tachycardia Syndrome.Cureus · 2026Article
- Patient perspectives on exercise among adults with postural orthostatic tachycardia syndrome: a mixed methods study.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Single-Electrode, Bidirectional Control of Heart Rate via Vagus Nerve Modulation in Rat Model.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Comprehensive Assessment of Autonomic Nervous System Profiles in Postural Orthostatic Tachycardia Syndrome Among Syncope, Chronic Fatigue, and Post-COVID-19 Patients.Diagnostics (Basel, Switzerland) · 2025Article
- Time-restricted eating improves quality of life, heart rate, and mitochondrial function in patients with postural orthostatic tachycardia syndrome. An open-label pilot study.Scientific reports · 2025Article
- Diastolic Blood Pressure Rise During Valsalva as a Surrogate for Sympathetic Activation to Identify Functional Hyperadrenergic Postural Tachycardia Syndrome.Research square · 2025Article
- Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Postural tachycardia syndrome (POTS) is a heterogeneous clinical syndrome that has gained increasing interest over the past few decades due to its increasing prevalence and clinical impact on health-related quality of life. POTS is clinically characterized by sustained excessive tachycardia upon standing that occurs in the absence of significant orthostatic hypotension and other medical conditions and or medications, and with chronic symptoms of orthostatic intolerance. POTS represents one of the most common presentations of syncope and presyncope secondary to autonomic dysfunction in emergency rooms and in cardiology, neurology, and primary care clinics. The most sensitive method to detect POTS is a detailed medical history, physical examination with orthostatic vital signs or brief tilt table test, and a resting 12-lead electrocardiogram. Additional diagnostic testing may be warranted in selected patients based on clinical signs. While the precise etiology remains unknown, the orthostatic tachycardia in POTS is thought to reflect convergence of multiple pathophysiological processes, as a final common pathway. Based on this, POTS is often described as a clinical syndrome consisting of multiple heterogeneous disorders, with several underlying pathophysiological processes proposed in the literature including partial sympathetic neuropathy, hyperadrenergic state, hypovolemia, mast cell activation, deconditioning, and immune-mediated. These clinical features often overlap, however, making it difficult to categorize individual patients. Importantly, POTS is not associated with mortality, with many patients improving to some degree over time after diagnosis and proper treatment. This review will outline the current understanding of diagnosis, pathophysiology, and prognosis in POTS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.