ArticleBMC neurology2018
A digital assessment system for evaluating kinetic tremor in essential tremor and Parkinson's disease.
Article in BMC neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- What the Tech? The Management of Neurological Dysfunction Through the Use of Digital Technology.Advances in experimental medicine and biology · 2021Pooled it
- Essential Tremor and Digital Biomarkers: A Scoping Review Using the TRACE Framework to Map Readiness for Clinical Trials and Routine Practice.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- Transcranial static magnetic field stimulation of the primary motor cortex in essential tremor: a randomized pilot study.NPJ Parkinson's disease · 2025Article
- Clinical Applications and Measurement Properties of the Digitized Archimedes Spiral Drawing Test: A Scoping Review.Movement disorders clinical practice · 2025Article
- Modern Phenomenology of Tremor: How Novel Technology Can Assist in the Diagnosis of Tremor.Movement disorders clinical practice · 2025Article
- Intelligent devices for assessing essential tremor: a comprehensive review.Journal of neurology · 2024Review
- Automatic speech-based assessment to discriminate Parkinson's disease from essential tremor with a cross-language approach.NPJ digital medicine · 2024Article
- Video Motion Analysis as a Quantitative Evaluation Tool for Essential Tremor during Magnetic Resonance-Guided Focused Ultrasound Thalamotomy.Neurology international · 2023Article
- Utilizing a tablet-based artificial intelligence system to assess movement disorders in a prospective study.Scientific reports · 2023Article
- Article
- Does Cup-Grip Type Affect Tremor among People with Essential Tremor?Sensors (Basel, Switzerland) · 2021Article
- Screening of Parkinson's Disease Using Geometric Features Extracted from Spiral Drawings.Brain sciences · 2021Article
- Drawing Direction Effect on a Task's Performance Characteristics among People with Essential Tremor.Sensors (Basel, Switzerland) · 2021Article
- Assessment of Smartphone-Based Spiral Tracing in Multiple Sclerosis Reveals Intra-Individual Reproducibility as a Major Determinant of the Clinical Utility of the Digital Test.Frontiers in medical technology · 2021Article
- Wearable Peripheral Electrical Stimulation Devices for the Reduction of Essential Tremor: A Review.IEEE access : practical innovations, open solutions · 2021Article
- A Mobile Application for Smart Computer-Aided Self-Administered Testing of Cognition, Speech, and Motor Impairment.Sensors (Basel, Switzerland) · 2020Article
- Multi-Dimensional, Short-Timescale Quantification of Parkinson's Disease and Essential Tremor Motor Dysfunction.Frontiers in neurology · 2020Article
- A Multimodal Approach to the Quantification of Kinetic Tremor in Parkinson's Disease.Sensors (Basel, Switzerland) · 2019Article
- Automatic Analysis of Archimedes' Spiral for Characterization of Genetic Essential Tremor Based on Shannon's Entropy and Fractal Dimension.Entropy (Basel, Switzerland) · 2018Article
- The difference in visuomotor feedback velocity control during spiral drawing between Parkinson's disease and essential tremor.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSpiral drawing on papers is a common tremor evaluation tool for diagnosing patients with essential tremor (ET) or Parkinson's disease (PD). No standard drawing methods and parameters that use graphic tablets are yet available for objective evaluation.
methodsThis study established a tremor assessment system for tremor severity by using graphic tablets. Twelve patients with ET and twelve patients with PD were tested to establish system algorithms, and six additional patients were tested with the developed system to evaluate its performance. The patients also performed spiral drawing with three guiding paradigms on a graphic tablet: traced along a given spiral (S1), performed freehand drawing (S2), and traced along a guiding point (S3). Three parameters were calculated to quantify tremor severity: the means of radial difference per radian (|dr/dθ|), the means of radial difference per second (|dr/dt|), and the area under curve (AUC) of the frequency spectrum of the velocity. Each patient's drawing was also evaluated using a visual rating scale (VRS) by experienced physicians. The interrater reliability was examined to identify the most consistent test paradigm.
resultsThe parameter |dr/dθ| and AUC correlated well with the VRS (R > 0.8) in S1, S2 and S3 tests. The S1 test presented the best interrater reliability (Weighted Kappa coefficient, k = 0.80) among three tests. The Weighted Kappa coefficients are 0.67 and 0.71 in S2 and S3 tests, respectively.
conclusionsWe developed three different guiding paradigms for spiral drawing on a digital graphic tablet for clinical tests. Three parameters were calculated to represent the tremor severity in spiral drawing and used to quantify temporal and spatial characteristics of tremor, and provided good correlation with current clinical assessments. The test "traced along a given spiral" is recommended due to its good interrater reliability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.