Evidence map›Paper›PMID 29523091›Full record

ArticleBMC nephrology2018

Membranous nephropathy succeeding autologous hematopoietic stem cell transplant: a case report.

Sanda Mrabet, Narjess Ben Aicha, Nihed Abdessayed, Moncef Mokni, Abdellatif Achour

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Review
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sanda MrabetDepartment of Nephrology, Dialysis and transplantation. Sahloul university Hospital, Sousse, Tunisia. snaiida@yahoo.fr.ORCID 0000-0002-9552-3650
Narjess Ben AichaDepartment of Nephrology, Dialysis and transplantation. Sahloul university Hospital, Sousse, Tunisia.
Nihed AbdessayedDepartment of Pathology, Farhat Hached University Hospital, Sousse, Tunisia.
Moncef MokniDepartment of Pathology, Farhat Hached University Hospital, Sousse, Tunisia.
Abdellatif AchourDepartment of Nephrology, Dialysis and transplantation. Sahloul university Hospital, Sousse, Tunisia.
Hôpital Sahloul · TNHôpital Farhat Hached · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMembranous nephropathy (MN), the leading cause of nephrotic syndrome in adults, is characterized by the deposition of subepithelial immune deposits. Most of the cases are primary, while only approximately 25% of the cases are secondary to some known diseases. Recently, MN has been considered to be a possible presentation of chronic graft-versus-host disease (GVHD) of the kidney in allogeneic hematopoietic stem cell transplantation (HSCT) patients. In autologous HSCT populations, there have been scarce reports of associated MN, as a result of immune dysregulation leading to systemic autoimmunity and miming chronic GVHD. CASE PRESENTATION: We report an exceptional case of MN associated to an acute renal failure occurring within days following an autologous HSCT indicated by multiple myeloma. There was no evidence of GVHD or myeloma relapse. A complete remission of nephrotic syndrome with normalization of renal function were rapidly obtained by corticosteroid therapy.

conclusionThis is the first published case of acute renal failure due to MN occurring in the acute phase of an autologous HSCT. These findings support the antibodymediated autoimmune glomerular disease.

Indexed as

Glomerulonephritis, MembranousHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedTransplantation, AutologousAutologous hematopoietic stem cell transplantationGlomerulonephritisGraft-vs-host diseaseMembranous nephropathy

Identifiers

PMID29523091
PMCPMC5845168
OpenAlexW2790469975

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.