Evidence map›Paper›PMID 29523073›Full record

ArticleBMC cardiovascular disorders2018

Association between admission anemia and long-term mortality in patients with acute myocardial infarction: results from the MONICA/KORA myocardial infarction registry.

Miriam Giovanna Colombo, Inge Kirchberger, Ute Amann, Margit Heier, Christian Thilo, Bernhard Kuch, Annette Peters, Christa Meisinger

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC cardiovascular disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. The Negative Influence and Adverse Outcome of Red Blood Cell Transfusion in Contemporary Percutaneous Coronary Interventions.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Review
  3. Article
  4. Living with a transplanted liver is associated with cytopenias: a nationwide cohort study.Frontiers in gastroenterology (Lausanne, Switzerland) · 2025
    Article
  5. Article
  6. Interaction between anemia and renal dysfunction in relation to long-term survival following acute myocardial infarction.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
  7. The treatment of chronic anemia in heart failure: a global approach.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Miriam Giovanna ColomboMONICA/KORA Myocardial Infarction Registry, Central Hospital of Augsburg, Augsburg, Germany. miriam.colombo@helmholtz-muenchen.de.ORCID 0000-0003-2814-1000
Inge KirchbergerMONICA/KORA Myocardial Infarction Registry, Central Hospital of Augsburg, Augsburg, Germany.
Ute AmannMONICA/KORA Myocardial Infarction Registry, Central Hospital of Augsburg, Augsburg, Germany.
Margit HeierMONICA/KORA Myocardial Infarction Registry, Central Hospital of Augsburg, Augsburg, Germany.
Christian ThiloDepartment of Internal Medicine I - Cardiology, Central Hospital of Augsburg, Augsburg, Germany.
Bernhard KuchDepartment of Internal Medicine I - Cardiology, Central Hospital of Augsburg, Augsburg, Germany.
Annette PetersInstitute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Christa MeisingerMONICA/KORA Myocardial Infarction Registry, Central Hospital of Augsburg, Augsburg, Germany.
University Hospital Augsburg · DEHelmholtz Zentrum München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have shown that the presence of anemia is associated with increased short- and long-term outcomes in patients with acute myocardial infarction (AMI). This study aims at examining the impact of admission anemia on long-term, all-cause mortality following AMI in patients recruited from a population-based registry. Contrary to most prior studies, we distinguished between patients with mild and moderate to severe anemia.

methodsThis prospective study was conducted in 2011 patients consecutively hospitalized for AMI that occurred between January 2005 and December 2008. Patients who survived more than 28 days after AMI were followed up until December 2011. Hemoglobin (Hb) concentration was measured at hospital admission and classified according to the World Health Organization (WHO). Mild anemia was defined as Hb concentration of 11 to < 12 g/dL in women and 11 to < 13 g/dL in men; moderate to severe anemia as Hb concentration of < 11 g/dL. Adjusted Cox regression models were calculated to compare survival in patients with and without anemia.

resultsMild anemia and moderate to severe anemia was found in 183 (9.1%) and 100 (5%) patients, respectively. All-cause mortality after a median follow-up time of 4.2 years was 11.9%. The Cox regression analysis showed significantly increased mortality risks in both patients with mild (HR 1.74, 95% CI 1.23-2.45) and moderate to severe anemia (HR 2.05, 95% CI 1.37-3.05) compared to patients without anemia.

conclusionThis study shows that anemia adversely affects long-term survival following AMI. However, further studies are needed to confirm that anemia can solely explain worse long-term outcomes after AMI.

Indexed as

Patient AdmissionAdultAgedAnemiaBiomarkersFemaleGermanyHealth StatusHemoglobinsHumansMaleMiddle AgedMyocardial InfarctionPrognosisProspective StudiesRegistriesBiomarkersHemoglobinsAnemiaHemoglobinMortalityMyocardial infarction

Identifiers

PMID29523073
PMCPMC5845173
OpenAlexW2798267638

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.