Evidence map›Paper›PMID 29522900›Full record

ReviewGenomics, proteomics & bioinformatics2018

Deep Learning and Its Applications in Biomedicine.

Chensi Cao, Feng Liu, Hai Tan, Deshou Song, Wenjie Shu, Weizhong Li, Yiming Zhou, Xiaochen Bo, Zhi Xie

Open access · goldAbstract readReview
In one paragraph

Review in Genomics, proteomics & bioinformatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed
23.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 618 citations in OpenAlex.

  1. Trial
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  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. AI-Driven TENGs for Self-Powered Smart Sensors and Intelligent Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Tendon regeneration deserves better: focused review onFrontiers in bioengineering and biotechnology · 2025
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chensi CaoCapitalBio Corporation, Beijing 102206, China.
Feng LiuDepartment of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Hai TanState Key Lab of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 500040, China.
Deshou SongState Key Lab of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 500040, China.
Wenjie ShuDepartment of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Weizhong LiZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 500040, China.
Yiming ZhouCapitalBio Corporation, Beijing 102206, China; Department of Biomedical Engineering, Medical Systems Biology Research Center, Tsinghua University School of Medicine, Beijing 100084, China. Electronic address: yimingzhou@capitalbio.com.
Xiaochen BoDepartment of Biotechnology, Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address: boxc@bmi.ac.cn.
Zhi XieState Key Lab of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 500040, China. Electronic address: xiezh8@sysu.edu.cn.
Sun Yat-sen University · CNBeijing Radiation Center · CNBeijing VDJBio (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in biological and medical technologies have been providing us explosive volumes of biological and physiological data, such as medical images, electroencephalography, genomic and protein sequences. Learning from these data facilitates the understanding of human health and disease. Developed from artificial neural networks, deep learning-based algorithms show great promise in extracting features and learning patterns from complex data. The aim of this paper is to provide an overview of deep learning techniques and some of the state-of-the-art applications in the biomedical field. We first introduce the development of artificial neural network and deep learning. We then describe two main components of deep learning, i.e., deep learning architectures and model optimization. Subsequently, some examples are demonstrated for deep learning applications, including medical image classification, genomic sequence analysis, as well as protein structure classification and prediction. Finally, we offer our perspectives for the future directions in the field of deep learning.

Indexed as

AlgorithmsDiagnostic ImagingMachine LearningNeural Networks, ComputerComputational BiologyGenomicsHumansImage Interpretation, Computer-AssistedProteinsProtein Structure, SecondaryProteinsBig dataBioinformaticsBiomedical informaticsDeep learningHigh-throughput sequencingMedical image

Identifiers

PMID29522900
PMCPMC6000200
OpenAlexW2789367970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.