Evidence map›Paper›PMID 29522754›Full record

ArticleExperimental cell research2018

The formation of giant plasma membrane vesicles enable new insights into the regulation of cholesterol efflux.

Alanna Sedgwick, M Olivia Balmert, Crislyn D'Souza-Schorey

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental cell research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Pathways and Mechanisms of Cellular Cholesterol Efflux-Insight From Imaging.Frontiers in cell and developmental biology · 2022
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alanna SedgwickDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556-0369, USA.
M Olivia BalmertDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556-0369, USA.
Crislyn D'Souza-SchoreyDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556-0369, USA. Electronic address: cdsouzas@nd.edu.
University of Notre Dame · US

Funding

Molecular Mechanisms of Cell InvasionR01CA115316 · NCI · UNIVERSITY OF NOTRE DAME · PI D'SOUZA-SCHOREY, CRISLYN · 2011 to 2016
$1.5M
NCI NIH HHS R01 CA115316
6 · The paper itself

Abstract

Aberrant cellular cholesterol accumulation contributes to the pathophysiology of many diseases including neurodegenerative disorders such as Niemann-Pick Type C (NPC) and Alzheimer's Disease

Indexed as

Biological TransportCell LineCell MembraneCholesterolExocytosisExtracellular VesiclesHumansLipid MetabolismOptical ImagingOrganelle SizeCholesterolCholesterol effluxCytoskeletonGiant plasma membrane vesiclesNiemann-Pick Type C

Identifiers

PMID29522754
PMCPMC6652231
OpenAlexW2789916856

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.