Trial reportPloS one2018
Impact of a Family Clinic Day intervention on paediatric and adolescent appointment adherence and retention in antiretroviral therapy: A cluster randomized controlled trial in Uganda.
Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Systematic review: Development of a person-centered care framework within the context of HIV treatment settings in sub-Saharan Africa.Tropical medicine & international health : TM & IH · 2022Pooled it
- Pooled it
- Interventions to improve early retention of patients in antiretroviral therapy programmes in sub-Saharan Africa: A systematic review.PloS one · 2022Pooled it
- Trial
- Reimagining Paediatric HIV Care: Centering Infants and Young Children in Optimized, Integrated Models of Care.Journal of the International AIDS Society · 2026Article
- Return to care of children and adolescents living with HIV who missed their clinic visits or were lost to follow-up: a continuous quality improvement study in Uganda.BMJ open quality · 2025Article
- Exploring Psychosocial and Economic Support for Children with HIV/AIDS: Perspectives of Health and Community Workers in the Katuba Health Zone, Lubumbashi.ClinicoEconomics and outcomes research : CEOR · 2025Article
- Article
- Presence of Teen Clubs and its Association with Clinic Attendance among Adolescents Living with HIV in Tanzania: A Retrospective Cohort Study.The East African health research journal · 2023Article
- The question of the question: impactful implementation science to address the HIV epidemic.Journal of the International AIDS Society · 2022Article
- A Review of Interventions to Enhance HIV Medication Adherence.Current HIV/AIDS reports · 2021Review
- Social support, gender and pill burden influence viral load suppression among HIV-infected adolescents and young adults in rural south-western Uganda.Vulnerable children and youth studies · 2021Article
- Psychosocial support interventions for improved adherence and retention in ART care for young people living with HIV (10-24 years): a scoping review.BMC public health · 2020Article
- 'There are no more secrets': acceptability of a family-centered model of care for HIV positive children in Eswatini.BMC health services research · 2020Article
- Viral suppression among children and their caregivers living with HIV in western Kenya.Journal of the International AIDS Society · 2019Article
- A Facility-based Family Support Intervention to Improve Treatment Outcomes for Adolescents on Antiretroviral Therapy in the Cape Metropole, South Africa.Journal of the International Association of Providers of AIDS CareArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn 2013, Uganda adopted a test-and-treat policy for HIV patients 15 years or younger. Low retention rates among paediatric and adolescent antiretroviral therapy (ART) initiates could severely limit the impact of this new policy. This evaluation tested the impact of a differentiated care model called Family Clinic Day (FCD), a family-centered appointment scheduling and health education intervention on patient retention and adherence to monthly appointment scheduling.
methodsWe conducted a cluster randomized controlled trial, from October 2014 to March 2015. Forty-six facilities were stratified by implementing partner and facility type and randomly assigned to the control or intervention arm. Primary outcomes included the proportion of patients retained in care at 6 months and the proportion adherent to their appointment schedule at last study period scheduled visit. Data collection occurred retrospectively in May 2015. Six patient focus group discussions and 17 health workers interviews were conducted to understand perspectives on FCD successes and challenges.
resultsA total of 4,715 paediatric and adolescent patient records were collected, of which 2,679 (n = 1,319 from 23 control facilities and 1,360 from 23 intervention facilities) were eligible for inclusion. The FCD did not improve retention (aOR 1.11; 90% CI 0.63-1.97, p = 0.75), but was associated with improved adherence to last appointment schedule (aOR 1.64; 90% CI 1.27-2.11, p<0.001). Qualitative findings suggested that FCD patients benefited from health education and increased psychosocial support.
conclusionFCD scale-up in Uganda may be an effective differentiated care model to ensure patient adherence to ART clinic appointment schedules, a key aspect necessary for viral load suppression. Patient health outcomes may also benefit following an increase in knowledge based on health education, and peer support. Broad challenges facing ART clinics, such as under-staffing and poor filing systems, should be addressed in order to improve patient care.
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