Evidence map›Paper›PMID 29522441›Full record

ArticleInternational journal of molecular sciences2018

miR-146b Inhibits Glucose Consumption by Targeting IRS1 Gene in Porcine Primary Adipocytes.

Yan-Ling Zhu, Ting Chen, Jia-Li Xiong, Di Wu, Qian-Yun Xi, Jun-Yi Luo, Jia-Jie Sun, Yong-Liang Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. The Role ofInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yan-Ling ZhuCollege of Animal Science, Guangdong Provincial Key Laboratory of Animal Nutrition Control, South China Agricultural University, Guangzhou 510642, China. Kerryju27@163.com.
Ting ChenCollege of Animal Science, Guangdong Provincial Key Laboratory of Animal Nutrition Control, South China Agricultural University, Guangzhou 510642, China. allinchen@scau.edu.cn.
Jia-Li XiongCollege of Animal Science, Guangdong Provincial Key Laboratory of Animal Nutrition Control, South China Agricultural University, Guangzhou 510642, China. XJL00LJX@163.com.
Di WuCollege of Animal Science, Guangdong Provincial Key Laboratory of Animal Nutrition Control, South China Agricultural University, Guangzhou 510642, China. diwu@huskers.unl.edu.
Qian-Yun XiCollege of Animal Science, Guangdong Provincial Key Laboratory of Animal Nutrition Control, South China Agricultural University, Guangzhou 510642, China. xqy0228@163.com.
Jun-Yi LuoCollege of Animal Science, Guangdong Provincial Key Laboratory of Animal Nutrition Control, South China Agricultural University, Guangzhou 510642, China. luojunyi@scau.edu.cn.ORCID 0000-0002-1060-4081
Jia-Jie SunCollege of Animal Science, Guangdong Provincial Key Laboratory of Animal Nutrition Control, South China Agricultural University, Guangzhou 510642, China. jiajiesun@scau.edu.cn.
Yong-Liang ZhangCollege of Animal Science, Guangdong Provincial Key Laboratory of Animal Nutrition Control, South China Agricultural University, Guangzhou 510642, China. zhangyl@scau.edu.cn.
South China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose tissue plays an important role in energy metabolism. Adipose dysfunction is closely related to obesity and type II diabetes. Glucose uptake is the key step for fat synthesis in adipocyte. miRNAs have been proven to play a crucial role in adipocyte differentiation, adipogenesis and glucose homeostasis. In this paper, we firstly reported that miR-146b decreased glucose consumption by up-regulating miR-146b in a porcine primary adipocyte model, while the inhibitor of endogenous miR-146b rescued the reduction. Then, miR-146b was predicated to target

Indexed as

AdipocytesAdipogenesisAdipose TissueAnimalsBase SequenceGlucoseGlucose Transporter Type 4Insulin Receptor Substrate ProteinsLipogenesisMicroRNAsPrimary Cell CultureSwineUp-RegulationGlucoseGlucose Transporter Type 4Insulin Receptor Substrate ProteinsMicroRNAsadipocyteglucose consumptionGLUT4IRS1miR-146b

Identifiers

PMID29522441
PMCPMC5877644
OpenAlexW2790007633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.