ArticleCerebral cortex (New York, N.Y. : 1991)2019
Toward Leveraging Human Connectomic Data in Large Consortia: Generalizability of fMRI-Based Brain Graphs Across Sites, Sessions, and Paradigms.
Article in Cerebral cortex (New York, N.Y. : 1991), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of the relationship between magnetic resonance imaging based resting-state and structural networks in the rodent brain.Frontiers in neuroscience · 2023Pooled it
- Big Data, Small Bias: Harmonizing Diffusion MRI-Based Structural Connectomes to Mitigate Site-Related Bias in Data Integration.Human brain mapping · 2025Article
- Brain network dynamics predict moments of surprise across contexts.Nature human behaviour · 2025Article
- Developmental perspectives on the origins of psychotic disorders: The need for a transdiagnostic approach.Development and psychopathology · 2024Review
- Aberrant Flexibility of Dynamic Brain Network in Patients with Autism Spectrum Disorder.Bioengineering (Basel, Switzerland) · 2024Article
- Aberrant resting-state co-activation network dynamics in major depressive disorder.Translational psychiatry · 2024Article
- The roles, challenges, and merits of the p value.Patterns (New York, N.Y.) · 2023Review
- Traveling Subject-Informed Harmonization Increases Reliability of Brain Diffusion Tensor and Neurite Mapping.Aging and disease · 2023Article
- Early development of the functional brain network in newborns.Brain structure & function · 2023Article
- Effects of phase encoding direction on test-retest reliability of human functional connectome.NeuroImage · 2023Article
- Blockchain-enabled immutable, distributed, and highly available clinical research activity logging system for federated COVID-19 data analysis from multiple institutions.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Evaluating test-retest reliability and sex-/age-related effects on temporal clustering coefficient of dynamic functional brain networks.Human brain mapping · 2023Article
- Linked brain connectivity patterns with psychopathological and cognitive phenotypes in drug-naïve first-episode schizophrenia.Psychoradiology · 2022Article
- Cerebello-Thalamo-Cortical Hyperconnectivity Classifies Patients and Predicts Long-Term Treatment Outcome in First-Episode Schizophrenia.Schizophrenia bulletin · 2022Article
- Existence of Functional Connectome Fingerprint during Infancy and Its Stability over Months.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- A guide to the measurement and interpretation of fMRI test-retest reliability.Current opinion in behavioral sciences · 2021Article
- Article
- Cross-paradigm connectivity: reliability, stability, and utility.Brain imaging and behavior · 2021Article
- Age-Related Decrease in Default-Mode Network Functional Connectivity Is Accelerated in Patients With Major Depressive Disorder.Frontiers in aging neuroscience · 2021Article
- Prediction of trust propensity from intrinsic brain morphology and functional connectome.Human brain mapping · 2021Article
Corrections and comments
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Authors and funding
24 authors.
Funding
Abstract
While graph theoretical modeling has dramatically advanced our understanding of complex brain systems, the feasibility of aggregating connectomic data in large imaging consortia remains unclear. Here, using a battery of cognitive, emotional and resting fMRI paradigms, we investigated the generalizability of functional connectomic measures across sites and sessions. Our results revealed overall fair to excellent reliability for a majority of measures during both rest and tasks, in particular for those quantifying connectivity strength, network segregation and network integration. Processing schemes such as node definition and global signal regression (GSR) significantly affected resulting reliability, with higher reliability detected for the Power atlas (vs. AAL atlas) and data without GSR. While network diagnostics for default-mode and sensori-motor systems were consistently reliable independently of paradigm, those for higher-order cognitive systems were reliable predominantly when challenged by task. In addition, based on our present sample and after accounting for observed reliability, satisfactory statistical power can be achieved in multisite research with sample size of approximately 250 when the effect size is moderate or larger. Our findings provide empirical evidence for the generalizability of brain functional graphs in large consortia, and encourage the aggregation of connectomic measures using multisite and multisession data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.