Evidence map›Paper›PMID 29520981›Full record

ArticlePhysiological reports2018

Metabolic effects of Tofogliflozin are efficiently enhanced with appropriate dietary carbohydrate ratio and are distinct from carbohydrate restriction.

Shiori Ito, Toshio Hosaka, Wataru Yano, Takahiro Itou, Misako Yasumura, Yukari Shimizu, Hideyuki Kobayashi, Takashi Nakagawa, Keisuke Inoue, Sohei Tanabe and 2 more

Abstract read
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shiori ItoTokyo New Drug Research Laboratories, Kowa Company, LTD., Tokyo, Japan.
Toshio HosakaThird Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, Kyorin University School of Medicine, Tokyo, Japan.
Wataru YanoTokyo New Drug Research Laboratories, Kowa Company, LTD., Tokyo, Japan.
Takahiro ItouTokyo New Drug Research Laboratories, Kowa Company, LTD., Tokyo, Japan.
Misako YasumuraTokyo New Drug Research Laboratories, Kowa Company, LTD., Tokyo, Japan.
Yukari ShimizuTokyo New Drug Research Laboratories, Kowa Company, LTD., Tokyo, Japan.
Hideyuki KobayashiTokyo New Drug Research Laboratories, Kowa Company, LTD., Tokyo, Japan.
Takashi NakagawaTokyo New Drug Research Laboratories, Kowa Company, LTD., Tokyo, Japan.
Keisuke InoueTokyo New Drug Research Laboratories, Kowa Company, LTD., Tokyo, Japan.
Sohei TanabeTokyo New Drug Research Laboratories, Kowa Company, LTD., Tokyo, Japan.
Takuma KondoThird Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, Kyorin University School of Medicine, Tokyo, Japan.
Hitoshi IshidaThird Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, Kyorin University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium-glucose cotransporter 2 inhibitors (SGLT2i) exert their antidiabetic effects by promoting urinary glucose excretion. Nutrition therapy is obviously important, but little is known about the interactions between SGLT2i agents and carbohydrate restriction. Therefore, we studied these interactions using an obese diabetic animal model. KK-A

Indexed as

Diet, Carbohydrate-RestrictedAnimalsBenzhydryl CompoundsBlood GlucoseDiabetes Mellitus, Type 2Dietary CarbohydratesFatty AcidsGlucosidesHypoglycemic AgentsMaleMiceSodium-Glucose Transporter 2 Inhibitors6-((4-ethylphenyl)methyl)-3',4',5',6'-tetrahydro-6'-(hydroxymethyl)spiro(isobenzofuran-1(3H),2'-(2H)pyran)-3',4',5'-triolBenzhydryl CompoundsBlood GlucoseDietary CarbohydratesFatty AcidsGlucosidesHypoglycemic AgentsSodium-Glucose Transporter 2 InhibitorsLow-carbohydrate dietsodium-glucose cotransporter 2 inhibitor

Identifiers

PMID29520981
PMCPMC5843757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.