Evidence map›Paper›PMID 29520717›Full record

ReviewCurrent psychiatry reports2018

Presentation and Neurobiology of Anhedonia in Mood Disorders: Commonalities and Distinctions.

Sakina J Rizvi, Clare Lambert, Sidney Kennedy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current psychiatry reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Brain network localization of anhedonia.Translational psychiatry · 2026
    Article
  5. Article
  6. Exploring pleasure as a mediator of outcomes in music therapy.BMC complementary medicine and therapies · 2025
    Article
  7. Article
  8. AnbioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Article
  11. A missing link in affect regulation: the cerebellum.Social cognitive and affective neuroscience · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Chronic Stress Prevents Cortico-Accumbens Cue Encoding and Alters Conditioned Approach.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sakina J RizviLi Ka Shing Knowledge Institute, Arthur Sommer Rotenberg Suicide and Depression Studies Unit, St. Michael's Hospital, University of Toronto, 193 Yonge St, 6-009, Toronto, ON, M5B 1M8, Canada. rizvisa@smh.ca.
Clare LambertLi Ka Shing Knowledge Institute, Arthur Sommer Rotenberg Suicide and Depression Studies Unit, St. Michael's Hospital, University of Toronto, 193 Yonge St, 6-009, Toronto, ON, M5B 1M8, Canada.
Sidney KennedyLi Ka Shing Knowledge Institute, Arthur Sommer Rotenberg Suicide and Depression Studies Unit, St. Michael's Hospital, University of Toronto, 193 Yonge St, 6-009, Toronto, ON, M5B 1M8, Canada.
St. Michael's Hospital · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo focus on the clinical and behavioral presentation of anhedonia in mood disorders, as well as the differences and commonalities in the underlying neurocircuitry. RECENT

findingsEvidence suggests that depression is characterized by hypofunction of the reward system, while bipolar disorder manifests dysregulation of the behavioral activation system that increases goal-directed reward behavior. Importantly, strong evidence does not exist to suggest significant differences in anhedonia severity between depressed unipolar and bipolar patients, suggesting that there are more nuanced fluctuations in reward processing deficits in bipolar patients depending on their state. Both euthymic unipolar and bipolar patients frequently report residual reward dysfunction, which highlights the potential of reward processing deficits that give rise to the clinical symptom of anhedonia to be trait factors of mood disorders; however, the possibility that therapies are not adequately treating anhedonia could also explain the presence of residual symptoms. Reward processing represents a potential diagnostic and treatment marker for mood disorders. Further research should systematically explore the facets of reward processing in at-risk, affected, and remitted patients.

Indexed as

AnhedoniaBipolar DisorderBrainFunctional NeuroimagingHumansMajor Depressive DisorderMood DisordersResearchRewardAnhedoniaBipolar disorderMajor depressive disorderNeuroimagingReward processing

Identifiers

PMID29520717
OpenAlexW2790614084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.