Evidence map›Paper›PMID 29520687›Full record

ArticleLasers in medical science2018

Effect of 660 nm visible red light on cell proliferation and viability in diabetic models in vitro under stressed conditions.

S M Ayuk, N N Houreld, H Abrahamse

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06352372 (Safety and Efficacy of Transcranial Photobiomodulation), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06352372 phase2completednot on this mapstarted 2024, after this paper: background citation

Safety and Efficacy of Transcranial Photobiomodulation (tPBM) for Individuals With Autism Spectrum Disorder and Epileptiform Activity

TypeinterventionalSponsorRichard FryeRan2024 to 2026Enrolled6ConditionsAutism Spectrum Disorder, EEG With Periodic Abnormalities, Epilepsy, Neurodevelopmental DisordersArmsnoninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM)
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  8. Newly Synthesized CoFeInternational journal of molecular sciences · 2023
    Article
  9. Photobiomodulation at 660 nm promotes collagen synthesis via downregulation of HIF-1α expression without photodamage in human scleral fibroblasts in vitro in a hypoxic environment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  10. Article
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  14. Photobiomodulation at 830 nm Stimulates Migration, Survival and Proliferation of Fibroblast Cells.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S M AyukLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, 2028, South Africa.
N N HoureldLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, 2028, South Africa. nhoureld@uj.ac.za.
H AbrahamseLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, 2028, South Africa.
University of Johannesburg · ZA

Funding

South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation of South Africa (Grant No 98337) 98337
6 · The paper itself

Abstract

The current study evaluated the photobiomodulatory effect of visible red light on cell proliferation and viability in various fibroblast diabetic models in vitro, namely, unstressed normal (N) and stressed normal wounded (NW), diabetic wounded (DW), hypoxic wounded (HW) and diabetic hypoxic wounded (DHW). Cells were irradiated at a wavelength of 660 nm with a fluence of 5 J/cm

Indexed as

Low-Level Light TherapyCell LineCell MovementCell ProliferationCell SurvivalDiabetes ComplicationsFibroblastsHumansLightWound HealingDiabetesLaserPhotobiomodulationWound healing

Identifiers

PMID29520687
OpenAlexW2793481007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.