Evidence map›Paper›PMID 29520647›Full record

SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2018

Colonic Interposition After Adult Oesophagectomy: Systematic Review and Meta-analysis of Conduit Choice and Outcome.

Jade Brown, Wyn G Lewis, Antonio Foliaki, Geoffrey W B Clark, Guy R J C Blackshaw, David S Y Chan

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Outcomes of Gastric Conduit in Corrosive Esophageal Stricture: a Systematic Review and Meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Nutritional aspects and quality of life in gastroesophageal cancer patients that underwent colonic interposition.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026
    Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Management of Parastomal Recurrence Following Total Laryngectomy.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Impact of Anastomotic Leakage on Survival for Patients with Thoracic Esophageal Cancer Performed with Esophagectomy Followed by Right Colon Interposition.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jade BrownUniversity Hospital of Wales, Heath Park, Cardiff, Wales, CF14 4XN, UK.
Wyn G LewisUniversity Hospital of Wales, Heath Park, Cardiff, Wales, CF14 4XN, UK.
Antonio FoliakiUniversity Hospital of Wales, Heath Park, Cardiff, Wales, CF14 4XN, UK.
Geoffrey W B ClarkUniversity Hospital of Wales, Heath Park, Cardiff, Wales, CF14 4XN, UK.
Guy R J C BlackshawUniversity Hospital of Wales, Heath Park, Cardiff, Wales, CF14 4XN, UK.
David S Y ChanUniversity Hospital of Wales, Heath Park, Cardiff, Wales, CF14 4XN, UK. dcsy23@gmail.com.
University Hospital of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColonic interposition is a second-line option after oesophagectomy when a gastric neo-oesophagus is not viable. There is no consensus on the optimum anatomical colonic conduit (right or left), or route of placement (posterior mediastinal, retrosternal or subcutaneous). The aim of this review was to determine the optimum site and route of neo-oesophageal conduit after adult oesophagectomy.

methodsPubMed, MEDLINE, and the Cochrane Library (January 1985 to January 2017) were systematically searched for studies which reported outcomes following colonic interposition in adults. The outcome measures were overall morbidity and mortality.

resultsTwenty-seven observational studies involving 1849 patients [1177 males; median age (range) 60.5 (18-84) years] undergoing colonic interposition for malignant (n = 697) and benign (n = 1152) pathology were analysed. Overall pooled morbidity of left vs. right colonic conduit was 15.7% [95% CI (11.93-19.46), p < 0.001] and 18.7% [95% CI (15.58-21.82), p < 0.001] respectively. Overall pooled mortality of left vs. right colonic conduit was 6.5% [95% CI (4.55-8.51), p < 0.001] and 10.1% [95% CI (7.35-12.82), p < 0.001] respectively. Retrosternal route placement was associated with the lowest overall pooled morbidity and mortality of 9.2% [95% CI (6.48-11.99), p < 0.001] and 4.8% [95% CI (3.74-5.89), p < 0.001] respectively.

conclusionLeft colonic conduits placed retrosternally were safest.

Indexed as

EsophagectomySurgically-Created StructuresColonEsophageal NeoplasmsEsophagusHumansTransplantation, AutologousTreatment OutcomeColonic interposition

Identifiers

PMID29520647
OpenAlexW2790646416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.