Evidence map›Paper›PMID 29520549›Full record

ArticleEnvironmental science and pollution research international2018

Levels of urinary metabolites of four PAHs and cotinine determined in 1016 volunteers living in Central Italy.

Francesca Tombolini, Daniela Pigini, Giovanna Tranfo, Enrico Paci, Ilaria Carosi, Federico Marini, Lisa Bauleo, Carla Ancona, Francesco Forastiere

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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  8. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Francesca TomboliniDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, Research Area of Monte Porzio Catone (RM), INAIL Research, Via di Fontana Candida 1, 00040 Monteporzio Catone, Rome, Italy.
Daniela PiginiDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, Research Area of Monte Porzio Catone (RM), INAIL Research, Via di Fontana Candida 1, 00040 Monteporzio Catone, Rome, Italy.
Giovanna TranfoDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, Research Area of Monte Porzio Catone (RM), INAIL Research, Via di Fontana Candida 1, 00040 Monteporzio Catone, Rome, Italy. g.tranfo@inail.it.ORCID http://orcid.org/0000-0001-8973-6046
Enrico PaciDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, Research Area of Monte Porzio Catone (RM), INAIL Research, Via di Fontana Candida 1, 00040 Monteporzio Catone, Rome, Italy.
Ilaria CarosiMaster Degree Course in Analytical Chemistry, Rome University Sapienza, Rome, Italy.
Federico MariniDepartment of Analytical Chemistry, Rome University Sapienza, Rome, Italy.
Lisa BauleoDepartment of Epidemiology (RM), Lazio Regional Health Service, Rome, Italy.
Carla AnconaDepartment of Epidemiology (RM), Lazio Regional Health Service, Rome, Italy.
Francesco ForastiereDepartment of Epidemiology (RM), Lazio Regional Health Service, Rome, Italy.
Istituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycyclic aromatic hydrocarbons (PAH) are products of the incomplete combustion of organic materials, and exposure of the general population to PAH is ubiquitous. They are also present in tobacco smoke. Some PAH are classified as carcinogens. Urine samples from 747 non-smoking and 269 smoking subjects living in the same area of Central Italy were analyzed in order to determine reference values for PAHs exposure of a general population. The concentration of cotinine, urinary metabolite of nicotine was also measured in these samples in order to classify the subjects as smokers or not. The median concentration and 50th percentile in females was higher than in males for all metabolites; 1- and 2-hydroxynaphtalene (1-OHNAP and 2-OHNAP) and 1-hydroxypyrene (1-OHPy), are significantly higher in smokers; on the other side 3-hydroxybenzo[a]pyrene (3-OHBaPy) and 6-hydroxynitropyrene (6-OHNPy) do not correlate with the cotinine concentration.

Indexed as

AdultBiomarkersCarcinogensCotinineEnvironmental MonitoringFemaleHumansItalyMaleMiddle AgedNicotinePolycyclic Aromatic HydrocarbonsSmokingVolunteersBiomarkersCarcinogensCotinineNicotinePolycyclic Aromatic HydrocarbonsHPLC-MS/MSHuman biomonitoringOccupational exposurePAH urinary metabolitesPolycyclic aromatic hydrocarbons (PAH)Urinary cotinine

Identifiers

PMID29520549
OpenAlexW2792619881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.