Evidence map›Paper›PMID 29520480›Full record

ReviewCurrent cardiology reports2018

Clinical Phenotyping of Transthyretin Cardiac Amyloidosis with Bone-Seeking Radiotracers in Heart Failure with Preserved Ejection Fraction.

Wengen Chen, Van-Khue Ton, Vasken Dilsizian

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Amyloids and the Heart: An Update.Journal of clinical medicine · 2024
    Review
  3. Cardiac amyloidosis detection by early bisphosphonate (99mTc-HMDP) scintigraphy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  4. Review
  5. Review
  6. The prevalence of TTR cardiac amyloidosis among patients undergoing bone scintigraphy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Observational
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wengen ChenDepartment of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S. Greene Street, Baltimore, MD, 21201, USA. wchen5@umm.edu.
Van-Khue TonDepartment of Medicine, Division of Cardiology, Advanced Heart Failure, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD, 21201, USA.
Vasken DilsizianDepartment of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S. Greene Street, Baltimore, MD, 21201, USA.
University of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe two most common types of cardiac amyloidosis are caused by fibril deposits of immunoglobulin light chains (AL) and transthyretin (TTR), each with distinct prognosis and clinical management. Cardiac amyloidosis is under-recognized among heart failure patients with preserved ejection fraction (HFpEF). Bone-seeking tracers like RECENT

findingsThe clinical scope of cardiac amyloidosis among HFpEF patients and current literature supporting the use of bone-seeking tracers for TTR cardiac amyloidosis are presented. The differences of imaging techniques for cardiac amyloid and bone disease evaluation, bone tracer pharmacodynamics, and imaging interpretation criteria for cardiac amyloidosis diagnosis are discussed. Finally, a diagnostic algorithm to use bone scintigraphy in cardiac amyloidosis diagnosis among HFpEF patients is proposed. Bone scintigraphy with

Indexed as

Amyloid Neuropathies, FamilialCardiomyopathiesEchocardiographyHeartHeart FailureHumansRadionuclide ImagingRadiopharmaceuticalsStroke VolumeTechnetium Tc 99m PyrophosphateRadiopharmaceuticalsTechnetium Tc 99m Pyrophosphate99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD)99mTc-pyrophosphate (99mTc-PYP)AmyloidosisBone scintigraphyHeart failure with preserved ejection fractionLight chainTransthyretin

Identifiers

PMID29520480
OpenAlexW2793811513

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.