Evidence map›Paper›PMID 29520334›Full record

ArticleTranslational vision science & technology2018

A Tablet-Based Retinal Function Test in Neovascular Age-Related Macular Degeneration Eyes and At-Risk Fellow Eye.

Chi Yun Doreen Ho, Zhichao Wu, Andrew Turpin, David J Lawson, Chi D Luu, Allison M McKendrick, Robyn H Guymer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chi Yun Doreen HoCenter for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.
Zhichao WuCenter for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.
Andrew TurpinDepartment of Computing and Information Systems, University of Melbourne, Melbourne, Australia.
David J LawsonDepartment of Computing and Information Systems, University of Melbourne, Melbourne, Australia.
Chi D LuuCenter for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.
Allison M McKendrickDepartment of Optometry and Vision Sciences, University of Melbourne, Melbourne, Australia.
Robyn H GuymerCenter for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.
University of Melbourne · AUCentre for Eye Research Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the feasibility of a tablet-based application to detect changes in retinal sensitivity and correlations with underlying pathology in neovascular age-related macular degeneration (nAMD) eyes undergoing treatment and in at-risk fellow eyes.

methodParticipants with nAMD in at least one eye were recruited, examined, and imaged using spectral-domain optical coherence tomography (SD-OCT). Retinal sensitivity was measured within the central 5° at 12 locations using a customized test delivered on an iPad. Test points were superimposed on SD-OCT locations to investigate structure/function relationships.

resultsIncluded in the study were 53 nAMD eyes and 21 at-risk fellow eyes. In nAMD eyes, the mean retinal sensitivity was 24.1 ± 1.8 dB with reduced retinal sensitivity associated with the presence of atrophy (

conclusionThe tablet-based test of retinal sensitivity was able to be performed by an elderly cohort with nAMD. The ability to correlate differences in sensitivity with pathology is encouraging when considering using the tablet devices as a home monitoring tool with remote surveillance. Dual pathology often present with retinal fluid confounded our ability to correlate fluid with sensitivity. TRANSLATIONAL RELEVANCE: These findings highlight the potential of tablet-based devices in performing visual function measures as a home monitoring tool with remote surveillance for the earlier detection of nAMD.

Indexed as

age-related macular degenerationhome monitoringtablet-device

Identifiers

PMID29520334
PMCPMC5837668
OpenAlexW2790585032

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.