Evidence map›Paper›PMID 29520329›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2017

Probable REM-Sleep Behavior Disorder and Dysautonomic Symptoms in Essential Tremor.

Raquel Barbosa, Marcelo Mendonça, Filipa Ladeira, Rita Miguel, Paulo Bugalho

Open access · greenAbstract read
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Prevalence of Probable REM Sleep Behavior Disorder in Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Sleep Disorders in Patients with Essential Tremor.Current neurology and neuroscience reports · 2021
    Review
  9. Article
  10. Genetic Risk Factors for Essential Tremor: A Review.Tremor and other hyperkinetic movements (New York, N.Y.) · 2020
    Review
  11. Essential tremor: New advances.Clinical parkinsonism & related disorders · 2020
    Review
  12. Review
  13. Article
  14. Article
  15. Essential Tremor and Parkinson's Disease: Exploring the Relationship.Tremor and other hyperkinetic movements (New York, N.Y.) · 2018
    Review
  16. Is there a Premotor Phase of Essential Tremor?Tremor and other hyperkinetic movements (New York, N.Y.) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Raquel BarbosaNeurology Department, Hospital Egas Moniz - Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Marcelo MendonçaNeurology Department, Hospital Egas Moniz - Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Filipa LadeiraNeurology Department, Hospital Egas Moniz - Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Rita MiguelNeurology Department, Hospital Egas Moniz - Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Paulo BugalhoNeurology Department, Hospital Egas Moniz - Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Hospital de Egas Moniz · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Non-motor symptoms can be present in essential tremor (ET). We intend to assess the frequency of rapid eye movement (REM) sleep behavior disorder (RBD) and dysautonomic symptoms in ET patients and evaluate the differences between patients with ET and RBD (ET-RBD and ET without RBD [ET-nonRBD]). Methods: All ET patients were contacted by telephone. Autonomic symptoms were assessed using the Scales for Outcomes in Parkinson's Disease-Autonomic (SCOPA-AUT) questionnaire, and RBD symptoms with the RBD screening questionnaire (RBDSQ) using ≥5 as a cut-off for probable RBD (pRBD). Results: From 92 ET patients contacted, 53 (55% female) were included. The mean age at assessment was 73.6±19 years, and the average disease duration was 19.9±17.3 years. Fourteen patients (26.4%) had pRBD and 52 (98.1%) reported at least one autonomic symptom, the most prevalent being urinary symptoms (96%). The ET-RBD group had higher SCOPA-total and thermoregulatory scores than ET-nonRBD patients (13.9±9.6 vs. 7.7±5.1, p=0.017 and 2.5±2.0 vs. 0.9±1.6, p=0.001). There were no other differences between groups. Discussion: Our results suggest that pRBD is common in ET, and its presence is associated with dysautonomic symptoms. As these symptoms are known to be prodromal symptoms of Parkinson's disease (PD), we question if this patient subgroup has a higher risk of developing a synucleinopathy.

Indexed as

AgedCohort StudiesEssential TremorFemaleHumansMalePrimary DysautonomiasREM Sleep Behavior Disorderautonomic symptomsEssential tremornon-motor symptomsREM-sleep behavior disordersynucleinopathies

Identifiers

PMID29520329
PMCPMC5840316
OpenAlexW2779733274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.