Evidence map›Paper›PMID 29520269›Full record

ArticleFrontiers in immunology2018

Functional and Phenotypic Changes of Natural Killer Cells in Whole Blood during

Mathieu Garand, Martin Goodier, Olumuyiwa Owolabi, Simon Donkor, Beate Kampmann, Jayne S Sutherland

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 64 citations in OpenAlex.

  1. Tuberculosis treatment and cytotoxic immune signatures: a longitudinal study.Journal of clinical tuberculosis and other mycobacterial diseases · 2026
    Article
  2. Article
  3. Future Research Directions on Mycobacterium tuberculosis Proteins.Advances in experimental medicine and biology · 2026
    Review
  4. Review
  5. Article
  6. NK Cells: A Powerful Squad Versus SARS-CoV-2.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Loss of circulating CD8αbioRxiv : the preprint server for biology · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Clinical manifestations and immune response to tuberculosis.World journal of microbiology & biotechnology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mathieu GarandVaccines and Immunity Theme, Medical Research Council Unit, Fajara, Gambia.
Martin GoodierLondon School of Hygiene and Tropical Medicine, Bloomsbury, London, United Kingdom.
Olumuyiwa OwolabiVaccines and Immunity Theme, Medical Research Council Unit, Fajara, Gambia.
Simon DonkorVaccines and Immunity Theme, Medical Research Council Unit, Fajara, Gambia.
Beate KampmannVaccines and Immunity Theme, Medical Research Council Unit, Fajara, Gambia.
Jayne S SutherlandVaccines and Immunity Theme, Medical Research Council Unit, Fajara, Gambia.
MRC Unit the Gambia · GMLondon School of Hygiene & Tropical Medicine · GB

Funding

Medical Research Council MC_EX_MR/K011944/1Medical Research Council MC_UP_A900_1122Medical Research Council MC_UU_00026/2
6 · The paper itself

Abstract

Tuberculosis (TB) is still a global health concern, especially in resource-poor countries such as The Gambia. Defining protective immunity to TB is challenging: its pathogenesis is complex and involves several cellular components of the immune system. Recent works in vaccine development suggest important roles of the innate immunity in natural protection to TB, including natural killer (NK) cells. NK cells mediate cellular cytotoxicity and cytokine signaling in response to

Indexed as

AdolescentAdultAgedAntitubercular AgentsCell DegranulationCross-Sectional StudiesFollow-Up StudiesGambiaHumansImmunologic MemoryImmunophenotypingInterferon-gammaKiller Cells, NaturalLymphocyte ActivationLymphocyte SubsetsMiddle AgedAntitubercular AgentsInterferon-gammaTuberculosis VaccinesCD107aCD57Fc gamma receptor IIIaflow cytometryinnate memoryinterferon gammanatural killer cellsNKG2C

Identifiers

PMID29520269
PMCPMC5827559
OpenAlexW2789328644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.