Evidence map›Paper›PMID 29520193›Full record

ArticleKorean journal of radiology

Diagnostic Value of Volume-Based Fluorine-18-Fluorodeoxyglucose PET/CT Parameters for Characterizing Thyroid Incidentaloma.

Huazheng Shi, Zuguo Yuan, Zheng Yuan, Chunshan Yang, Jian Zhang, Yi Shou, Wenrui Zhang, Zhaofu Ping, Xin Gao, Shiyuan Liu

Abstract read
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. [European journal of nuclear medicine and molecular imaging · 2023
    Article
  4. Article
  5. Radiomics Analysis of [Diagnostics (Basel, Switzerland) · 2022
    Review
  6. Article
  7. Article
  8. Evaluating FocalNuclear medicine and molecular imaging · 2020
    Article
  9. Role of multi-modality functional imaging in differentiation between benign and malignant thyroidClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Huazheng ShiShanghai Universal Medical Imaging Diagnostic Center, Shanghai 200233, China.
Zuguo YuanDepartment of Chemoradiotherapy, Yinzhou People's Hospital, Ningbo 315100, China.
Zheng YuanShanghai Universal Medical Imaging Diagnostic Center, Shanghai 200233, China.
Chunshan YangShanghai Universal Medical Imaging Diagnostic Center, Shanghai 200233, China.
Jian ZhangShanghai Universal Medical Imaging Diagnostic Center, Shanghai 200233, China.
Yi ShouShanghai Universal Medical Imaging Diagnostic Center, Shanghai 200233, China.
Wenrui ZhangShanghai Universal Medical Imaging Diagnostic Center, Shanghai 200233, China.
Zhaofu PingShanghai Universal Medical Imaging Diagnostic Center, Shanghai 200233, China.
Xin GaoShanghai Universal Medical Imaging Diagnostic Center, Shanghai 200233, China.
Shiyuan LiuDepartment of Radiology, affiliated Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess clinical value of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) for differentiation of malignant from benign focal thyroid incidentaloma. Materials and Methods: This retrospective study included 99 patients with focal thyroid incidentaloma of 5216 non-thyroid cancer patients that had undergone PET/CT. PET/CT semi-quantitative parameters, volume-based functional parameters, metabolic tumor volume (MTV), and total lesion glycolysis (TLG) of thyroid incidentaloma were assessed. Receiver-operating characteristic (ROC) analysis was conducted and areas under the curve (AUC) were compared by Hanley and McNeil test to evaluate usefulness of maximum standardized uptake value (SUVmax), MTV and TLG, as markers for differentiating malignant from benign thyroid incidentalomas. Results: Of 99 thyroid incidentalomas, 64 (64.6%) were malignant and 35 (35.4%) were benign. Malignant thyroid incidentalomas were larger (1.8 cm vs. 1.3 cm, Conclusion: Volume-based PET/CT parameters could potentially have clinical value in differential diagnosis of thyroid incidentaloma along with SUVmax.

Indexed as

Positron Emission Tomography Computed TomographyAdultAgedAged, 80 and overArea Under CurveDiagnosis, DifferentialFemaleFluorodeoxyglucose F18GlycolysisHumansMaleMiddle AgedRetrospective StudiesROC CurveSensitivity and SpecificityThyroid NeoplasmsFluorodeoxyglucose F18FDG PET/CTFluorine-18-fluorodeoxyglucoseMetabolic tumor volumeThyroid incidentalomaThyroid neoplasmsTotal lesion glycolysis

Identifiers

PMID29520193
PMCPMC5840064

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.