Evidence map›Paper›PMID 29520170›Full record

ArticleThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology2018

Oxytocin produces thermal analgesia via vasopressin-1a receptor by modulating TRPV1 and potassium conductance in the dorsal root ganglion neurons.

Rafael Taeho Han, Han-Byul Kim, Young-Beom Kim, Kyungmin Choi, Gi Yeon Park, Pa Reum Lee, JaeHee Lee, Hye Young Kim, Chul-Kyu Park, Youngnam Kang and 2 more

Open access · diamondAbstract read
In one paragraph

Article in The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. TRPV1, Nrf2, and COVID-19: Could Oxytocin Have a Beneficial Role to Play?International archives of allergy and immunology · 2022
    Article
  3. Modulation of the thermosensory system by oxytocin.Frontiers in molecular neuroscience · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Rafael Taeho HanNeuroscience Research Institute and Department of Physiology, Korea University College of Medicine, Seoul 02841, Korea.
Han-Byul KimDepartment of Brain and Cognitive Sciences, College of Natural Sciences, Seoul National University, Seoul 03080, Korea.
Young-Beom KimNeuroscience Research Institute and Department of Physiology, Korea University College of Medicine, Seoul 02841, Korea.
Kyungmin ChoiNeuroscience Research Institute and Department of Physiology, Korea University College of Medicine, Seoul 02841, Korea.
Gi Yeon ParkDental Research Institute and Department of Neurobiology & Physiology, School of Dentistry, Seoul National University, Seoul 08826, Korea.
Pa Reum LeeDepartment of Brain and Cognitive Sciences, College of Natural Sciences, Seoul National University, Seoul 03080, Korea.
JaeHee LeeNeuroscience Research Institute and Department of Physiology, Korea University College of Medicine, Seoul 02841, Korea.
Hye Young KimNeuroscience Research Institute and Department of Physiology, Korea University College of Medicine, Seoul 02841, Korea.
Chul-Kyu ParkDepartment of Physiology, College of Medicine, Gachon University, Incheon 21936, Korea.
Youngnam KangDepartment of Neuroscience and Oral Physiology, Osaka University Graduate School of Dentistry, Osaka 565-0871, Japan.
Seog Bae OhDepartment of Brain and Cognitive Sciences, College of Natural Sciences, Seoul National University, Seoul 03080, Korea.
Heung Sik NaNeuroscience Research Institute and Department of Physiology, Korea University College of Medicine, Seoul 02841, Korea.
Korea University · KRSeoul National University · KROsaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have provided several lines of evidence that peripheral administration of oxytocin induces analgesia in human and rodents. However, the exact underlying mechanism of analgesia still remains elusive. In the present study, we aimed to identify which receptor could mediate the analgesic effect of intraperitoneal injection of oxytocin and its cellular mechanisms in thermal pain behavior. We found that oxytocin-induced analgesia could be reversed by d(CH

Indexed as

Dorsal root ganglionElectrophysiologyOxytocinPainVasopressin receptor

Identifiers

PMID29520170
PMCPMC5840076
OpenAlexW2790586369

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.