SynthesisClinical interventions in aging2018
Bone mineral density in patients with chronic heart failure: a meta-analysis.
Synthesis in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Association Between Serum Apolipoprotein B and Bone Mineral Density and the Effects of Cardiovascular Disease Mediation: Results From the NHANES 2011-2016 and a Mendelian Randomization Study.Reviews in cardiovascular medicine · 2025Article
- RBFOX2 induces osteogenic differentiation by Jph2 expression in MC3T3-E1 preosteoblast cells.Molecular biology reports · 2025Article
- Can N-terminal pro-B-type natriuretic peptide concentration on admission predict the functional independence measure at discharge in patients aged 75 years or older with postoperative proximal femur fracture?Journal of physical therapy science · 2025Article
- Vitamin D Deficiency in Patients Hospitalized for Heart Failure Living in the Tropics.International journal of heart failure · 2024Article
- Article
- Association between bone mineral density and cardiovascular disease in older adults.Frontiers in public health · 2023Article
- Lack of causal association between heart failure and osteoporosis: a Mendelian randomization study.BMC medical genomics · 2022Article
- Impact of heart failure severity on bone mineral density among older patients with heart failure.Heart and vessels · 2021Article
- Bone mineral density and risk of cardiovascular disease in men and women: the HUNT study.European journal of epidemiology · 2021Article
- Association between self-reported walking speed and calcaneal stiffness index in postmenopausal Japanese women.BMC geriatrics · 2020Article
- Secondary hyperparathyroidism and thoracic vertebral fractures in heart failure middle-aged patients: a 3-year prospective study.Journal of endocrinological investigation · 2020Article
- Impact of heart failure on functional recovery after hip fracture.Journal of physical therapy science · 2019Article
- Skeletal consequences of heart failure.Women's health (London, England)Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to verify the existing relationship between bone mineral density (BMD) and chronic heart failure (CHF) by meta-analysis.
methodsDatabases, including PubMed, Web of Science, and Chinese National Knowledge Infrastructure, published in English or Chinese up to February 28, 2017, were searched for studies on the association between CHF and BMD. Two independent reviewers collected the relevant articles. The standard mean deviation (SMD) and 95% confidence interval were calculated for BMD with fixed- and random-effect models. Subgroup and sensitivity analyses were also conducted.
resultsA total of six studies (552 CHF and 243 non-CHF patients) were included. The results indicated that the patients with CHF had a lower total BMD compared with the non-CHF patients. Similar effects were also observed for femoral neck, arm, leg, and trunk BMD. However, no difference was observed in the lumbar spine BMD. The SMD of total BMD in New York Heart Association classes I or II (NYHA I or II) patients was -0.62, while that in NYHA III or IV patients was -0.87, and the SMD of femoral bone mineral density in NYHA I or II patients was -0.47, while that in NYHA III or IV patients was -1.07. Moreover, vitamin D and parathyroid hormone (PTH) were also found to be associated with CHF.
conclusionPatients with CHF had a lower total BMD and femoral neck, arm, leg, or trochanter BMD than patients with non-CHF. Vitamin D reduced, whereas PTH increased, with the severity of CHF. The clinical significance of the present findings remains uncertain and should be confirmed by future studies.
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