Evidence map›Paper›PMID 29520098›Full record

ArticleScientific reports2018

Metaboloptics: Visualization of the tumor functional landscape via metabolic and vascular imaging.

Amy F Martinez, Samuel S McCachren, Marianne Lee, Helen A Murphy, Caigang Zhu, Brian T Crouch, Hannah L Martin, Alaattin Erkanli, Narasimhan Rajaram, Kathleen A Ashcraft and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

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  10. PGEProceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Amy F MartinezDepartment of Biomedical Engineering, Duke University, Durham, NC, USA. amyfmartinez@alumni.duke.edu.ORCID 0000-0002-8088-7398
Samuel S McCachrenDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Marianne LeeDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Helen A MurphyDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Caigang ZhuDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Brian T CrouchDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Hannah L MartinDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Alaattin ErkanliDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA.
Narasimhan RajaramDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.ORCID 0000-0003-1224-8567
Kathleen A AshcraftDuke University Medical Center, Durham, NC, USA.
Andrew N FontanellaDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Mark W DewhirstDuke University Medical Center, Durham, NC, USA.
Nirmala RamanujamDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.
Duke University · USDuke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many cancers adeptly modulate metabolism to thrive in fluctuating oxygen conditions; however, current tools fail to image metabolic and vascular endpoints at spatial resolutions needed to visualize these adaptations in vivo. We demonstrate a high-resolution intravital microscopy technique to quantify glucose uptake, mitochondrial membrane potential (MMP), and SO

Indexed as

Mammary Neoplasms, AnimalNeovascularization, PathologicAnimalsCell Line, TumorFemaleIntravital MicroscopyMiceMice, NudeOptical ImagingOrganometallic CompoundsTomography, X-Ray ComputedTumor MicroenvironmentOrganometallic Compoundstetramethyl rhodamine ethyl ester

Identifiers

PMID29520098
PMCPMC5843602
OpenAlexW2793326211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.