Evidence map›Paper›PMID 29520058›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2018

Histone deacetylases mediate GABA

John Peyton Bohnsack, Benjamin A Hughes, Todd K O'Buckley, Kamyra Edokpolor, Joyce Besheer, A Leslie Morrow

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

John Peyton BohnsackDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7178, USA.ORCID http://orcid.org/0000-0002-8713-4436
Benjamin A HughesBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7178, USA.
Todd K O'BuckleyBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7178, USA.
Kamyra EdokpolorBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7178, USA.
Joyce BesheerBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7178, USA.
A Leslie MorrowDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7178, USA. morrow@med.unc.edu.ORCID http://orcid.org/0000-0003-4441-956X
University of North Carolina at Chapel Hill · US

Funding

UNC ARC Information/Dissemination CoreP60AA011605 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A Herman · 2003 to 2026
$46.3M
UNC-CH NADIA Underage Drinking and Adult Brain Morphology in RatsU01AA020023 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CREWS, FULTON T · 2010 to 2024
$7.5M
UNC PREP in the Biomedical Sciences - Administrative SupplementR25GM089569 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBINSON, DONITA L, RODRIGUEZ-ROMAGUERA, JOSE · 2010 to 2024
$5.6M
MOLECULAR AND CELLULAR PATHOGENESIS IN ALCOHOLISMP50AA011605 · NIAAA · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI CREWS, FULTON T · 1998 to 2002
$4.9M
NIAAA NIH HHS P50 AA011605NIAAA NIH HHS P60 AA011605NIAAA NIH HHS U01 AA020023NIGMS NIH HHS R25 GM089569
6 · The paper itself

Abstract

Alcohol use disorders are chronic debilitating diseases characterized by severe withdrawal symptoms that contribute to morbidity and relapse. GABA

Indexed as

AcetylationAlcoholismAnimalsCerebral CortexEthanolHistone Deacetylase 2Histone Deacetylase 3Histone DeacetylasesHydroxamic AcidsLocomotionMaleMaze LearningPrefrontal CortexRatsReceptors, GABA-AReflex, RightingEthanolGabra1 protein, ratHdac2 protein, ratHistone Deacetylase 2Histone Deacetylase 3Histone DeacetylasesHydroxamic AcidsReceptors, GABA-Atrichostatin AZolpidem

Identifiers

PMID29520058
PMCPMC5983537
OpenAlexW2789384183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.